PMID- 38380196
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240222
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 16
IP  - 1
DP  - 2024 Jan
TI  - Nafamostat Mesylate for the Hypercoagulable State of SARS-CoV-2 With Renal 
      Replacement Therapy: A Case Report.
PG  - e52641
LID - 10.7759/cureus.52641 [doi]
LID - e52641
AB  - Being a dialysis patient is one of the risks for severe coronavirus disease 2019 
      (COVID-19) cases. In addition, there have been many reports of coagulation 
      abnormalities in severe COVID-19 cases; these also make dialysis management more 
      difficult. In this study, we report a case of severe COVID-19 in a hemodialysis 
      patient who had coagulation in the dialysis circuit with unfractionated heparin 
      (UFH), which could be managed without intracircuit obstruction when nafamostat 
      mesylate (NM) was used in combination with unfractionated heparin.
CI  - Copyright (c) 2024, Nakada et al.
FAU - Nakada, Koki
AU  - Nakada K
AD  - Emergency Department, Kyoto Prefectural University of Medicine, Kyoto, JPN.
FAU - Hirai, Daisuke
AU  - Hirai D
AD  - Nephrology Department, National Hospital Organization Kyoto Medical Center, 
      Kyoto, JPN.
FAU - Seta, Koichi
AU  - Seta K
AD  - Nephrology Department, National Hospital Organization Kyoto Medical Center, 
      Kyoto, JPN.
FAU - Nishiyama, Kei
AU  - Nishiyama K
AD  - Emergency and Critical Care Division, Niigata University, Niigata, JPN.
LA  - eng
PT  - Case Reports
DEP - 20240120
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10877068
OTO - NOTNLM
OT  - continuous renal replacement therapy (crrt)
OT  - covid-19
OT  - critical emergency medicine
OT  - heparin
OT  - hypercoagulation
OT  - intensive care unit
OT  - nafamostat
OT  - non-fractioned heparin
OT  - renal replacement therapy (rrt)
OT  - thrombosis
COIS- The authors have declared that no competing interests exist.
EDAT- 2024/02/21 11:15
MHDA- 2024/02/21 11:16
PMCR- 2024/01/20
CRDT- 2024/02/21 04:07
PHST- 2024/01/17 00:00 [accepted]
PHST- 2024/02/21 11:16 [medline]
PHST- 2024/02/21 11:15 [pubmed]
PHST- 2024/02/21 04:07 [entrez]
PHST- 2024/01/20 00:00 [pmc-release]
AID - 10.7759/cureus.52641 [doi]
PST - epublish
SO  - Cureus. 2024 Jan 20;16(1):e52641. doi: 10.7759/cureus.52641. eCollection 2024 
      Jan.