PMID- 38381323
OWN - NLM
STAT- Publisher
LR  - 20240221
IS  - 1931-7565 (Electronic)
IS  - 1931-7557 (Linking)
DP  - 2024 Feb 21
TI  - Association between patent foramen ovale and migraine: evidence from a 
      resting-state fMRI study.
LID - 10.1007/s11682-024-00868-9 [doi]
AB  - A relationship between migraine without aura (MO) and patent foramen ovale (PFO) 
      has been observed, but the neural basis underlying this relationship remains 
      elusive. Utilizing independent component analysis via functional magnetic 
      resonance imaging, we examined functional connectivity (FC) within and across 
      networks in 146 patients with MO (75 patients with and 71 patients without PFO) 
      and 70 healthy controls (35 patients each with and without PFO) to elucidate the 
      individual effects of MO and PFO, as well as their interaction, on brain 
      functional networks. The main effect of PFO manifested exclusively in the FC 
      among the visual, auditory, default mode, dorsal attention and salience networks. 
      Furthermore, the interaction effect between MO and PFO was discerned in brain 
      clusters of the left frontoparietal network and lingual gyrus network, as well as 
      the internetwork FC between the left frontoparietal network and the default mode 
      network (DMN), the occipital pole and medial visual networks, and the dorsal 
      attention and salience networks. Our findings suggest that the presence of a PFO 
      shunt in patients with MO is accompanied by various FC changes within and across 
      networks. These changes elucidate the intricate mechanisms linked to 
      PFO-associated migraines and provide a basis for identifying novel noninvasive 
      biomarkers.
CI  - (c) 2024. The Author(s).
FAU - Tang, Yusha
AU  - Tang Y
AUID- ORCID: 0000-0002-7089-0593
AD  - Department of Neurology, West China Hospital of Sichuan University, No. 37 Guoxue 
      Road, Chengdu, Sichuan Province, 610041, China.
FAU - Sun, Huaiqiang
AU  - Sun H
AD  - Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.
FAU - Plummer, Chris
AU  - Plummer C
AD  - Department of Neuroimaging, Swinburne University of Technology, Hawthorn, VIC, 
      Australia.
FAU - Vogrin, Simon J
AU  - Vogrin SJ
AD  - Department of Neuroimaging, Swinburne University of Technology, Hawthorn, VIC, 
      Australia.
AD  - Department of Neurosciences, St Vincent's Hospital, Melbourne, VIC, Australia.
FAU - Li, Hua
AU  - Li H
AD  - Department of Neurology, West China Hospital of Sichuan University, No. 37 Guoxue 
      Road, Chengdu, Sichuan Province, 610041, China.
FAU - Li, Yajiao
AU  - Li Y
AD  - Department of Cardiology, West China Hospital, Sichuan University, Chengdu, 
      China.
FAU - Chen, Lei
AU  - Chen L
AUID- ORCID: 0000-0001-5263-5540
AD  - Department of Neurology, West China Hospital of Sichuan University, No. 37 Guoxue 
      Road, Chengdu, Sichuan Province, 610041, China. leilei_25@126.com.
LA  - eng
GR  - 82271500/National Natural Science Foundation of China/
PT  - Journal Article
DEP - 20240221
PL  - United States
TA  - Brain Imaging Behav
JT  - Brain imaging and behavior
JID - 101300405
SB  - IM
OTO - NOTNLM
OT  - Functional connectivity
OT  - Independent component analysis
OT  - Migraine without aura
OT  - Patent foramen ovale
EDAT- 2024/02/21 12:43
MHDA- 2024/02/21 12:43
CRDT- 2024/02/21 11:13
PHST- 2024/02/15 00:00 [accepted]
PHST- 2024/02/21 12:43 [medline]
PHST- 2024/02/21 12:43 [pubmed]
PHST- 2024/02/21 11:13 [entrez]
AID - 10.1007/s11682-024-00868-9 [pii]
AID - 10.1007/s11682-024-00868-9 [doi]
PST - aheadofprint
SO  - Brain Imaging Behav. 2024 Feb 21. doi: 10.1007/s11682-024-00868-9.