PMID- 38383331 OWN - NLM STAT- MEDLINE DCOM- 20240223 LR - 20240306 IS - 1471-2431 (Electronic) IS - 1471-2431 (Linking) VI - 24 IP - 1 DP - 2024 Feb 22 TI - Effect of repetitive transcranial magnetic stimulation-assisted training on lower limb motor function in children with hemiplegic cerebral palsy. PG - 136 LID - 10.1186/s12887-024-04605-5 [doi] LID - 136 AB - OBJECTIVE: To explore the effect of repetitive transcranial magnetic stimulation (rTMS)-assisted training on lower limb motor function in children with hemiplegic cerebral palsy (HCP). METHOD: Thirty-one children with HCP who met the inclusion criteria were selected and randomly divided into a control group (n = 16) and an experimental group (n = 15). The control group received routine rehabilitation treatment for 30 min each time, twice a day, 5 days a week for 4 weeks. Based on the control group, the experimental group received rTMS for 20 min each time, once a day, 5 days a week for 4 weeks. The outcome measures included a 10-metre walk test (10MWT), a 6-minute walk distance (6MWD) test, D- and E-zone gross motor function measurements (GMFM), the symmetry ratio of the step length and stance time and the muscle tone of the triceps surae and the hamstrings (evaluated according to the modified Ashworth scale), which were obtained in both groups of children before and after treatment. RESULTS: After training, the 10MWT (P < 0.05), 6MWD (P < 0.01), GMFM (P < 0.001) and the symmetry ratio of the step length and stance time of the two groups were significantly improved (P < 0.05), there was more of an improvement in the experimental group compared with the control group. There was no significant change in the muscle tone of the hamstrings between the two groups before and after treatment (P > 0.05). After treatment, the muscle tone of the triceps surae in the experimental group was significantly reduced (P < 0.05), but there was no significant change in the control group (P > 0.05). CONCLUSION: Repetitive TMS-assisted training can improve lower limb motor function in children with HCP. CI - (c) 2024. The Author(s). FAU - He, Yan AU - He Y AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. AD - Capital Medical University School of Rehabilitation Medicine, No. 10 of Jiaomen North Street, Fengtai District, Beijing, 100068, China. FAU - Zhang, Qi AU - Zhang Q AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. zhangqi20220216@163.com. AD - Capital Medical University School of Rehabilitation Medicine, No. 10 of Jiaomen North Street, Fengtai District, Beijing, 100068, China. zhangqi20220216@163.com. FAU - Ma, Ting-Ting AU - Ma TT AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. AD - Capital Medical University School of Rehabilitation Medicine, No. 10 of Jiaomen North Street, Fengtai District, Beijing, 100068, China. FAU - Liang, Yan-Hua AU - Liang YH AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. AD - Capital Medical University School of Rehabilitation Medicine, No. 10 of Jiaomen North Street, Fengtai District, Beijing, 100068, China. FAU - Guo, Rong-Rong AU - Guo RR AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. FAU - Li, Xiao-Song AU - Li XS AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. AD - Capital Medical University School of Rehabilitation Medicine, No. 10 of Jiaomen North Street, Fengtai District, Beijing, 100068, China. FAU - Liu, Qian-Jin AU - Liu QJ AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. FAU - Feng, Tian-Yang AU - Feng TY AD - Department of Paediatric Physiotherapy, China Rehabilitation Research Center, Beijing Bo'ai Hospital, No. 10 of Jiaomen North street, Fengtai District, Beijing, 100068, China. LA - eng GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ GR - No.2021zx-13/Major Projected of China Rehabilitation Research Center/ PT - Journal Article PT - Randomized Controlled Trial DEP - 20240222 PL - England TA - BMC Pediatr JT - BMC pediatrics JID - 100967804 SB - IM MH - Child MH - Humans MH - *Cerebral Palsy MH - Hemiplegia/etiology MH - Lower Extremity MH - *Transcranial Magnetic Stimulation MH - Walking PMC - PMC10882917 OTO - NOTNLM OT - Hemiplegic cerebral palsy OT - Lower limb OT - Motor function OT - Rehabilitation OT - Repetitive transcranial magnetic stimulation COIS- All of the authors had no any personal, financial, commercial, or academic conflicts of interest separately. EDAT- 2024/02/22 00:43 MHDA- 2024/02/23 06:43 PMCR- 2024/02/22 CRDT- 2024/02/21 23:33 PHST- 2023/06/25 00:00 [received] PHST- 2024/01/30 00:00 [accepted] PHST- 2024/02/23 06:43 [medline] PHST- 2024/02/22 00:43 [pubmed] PHST- 2024/02/21 23:33 [entrez] PHST- 2024/02/22 00:00 [pmc-release] AID - 10.1186/s12887-024-04605-5 [pii] AID - 4605 [pii] AID - 10.1186/s12887-024-04605-5 [doi] PST - epublish SO - BMC Pediatr. 2024 Feb 22;24(1):136. doi: 10.1186/s12887-024-04605-5.