PMID- 38385563
OWN - NLM
STAT- MEDLINE
DCOM- 20240314
LR  - 20240314
IS  - 1553-2712 (Electronic)
IS  - 1069-6563 (Linking)
VI  - 31
IP  - 3
DP  - 2024 Mar
TI  - Utility of electroencephalography in toxin-induced seizures.
PG  - 249-255
LID - 10.1111/acem.14834 [doi]
AB  - INTRODUCTION: Toxin-induced seizures differ from seizures occurring in epilepsy 
      and have a high rate of complications. Electroencephalography (EEG) is routinely 
      obtained when there is concern for nonconvulsive status epilepticus (NCSE). The 
      purpose of this study was to characterize the typical findings after 
      toxin-induced seizures, assess the rate of epileptiform discharges and NCSE, and 
      identify any changes in management resulting from EEG. METHODS: Patients older 
      than 16 years who had an EEG during hospitalization for drug-induced seizure or 
      seizure-like activity were included. We reviewed 10 years of data (2013-2022) 
      across our hospital system (four community hospitals and one academic center). 
      Patients with a history of seizures and those with cardiac arrest prior to EEG 
      were excluded. The primary outcome was incidence of epileptiform discharges on 
      EEG. The secondary outcome was number of antiseizure medications (ASM) added 
      after EEG. RESULTS: A total of 256 encounters were screened with 83 patient 
      encounters included. A total of 53% (44/83) of EEGs showed some degree of 
      generalized slowing. A total of 2.4% (2/83) of cases had epileptiform activity on 
      EEG. No cases of nonconvulsive status were identified. No ASM was started in the 
      two cases where epileptiform discharges were identified. CONCLUSIONS: During 
      usual care of toxin-induced seizures, epileptiform discharges are uncommon.
CI  - (c) 2024 Society for Academic Emergency Medicine.
FAU - Sidlak, Alexander M
AU  - Sidlak AM
AUID- ORCID: 0000-0003-2181-8250
AD  - Emergency Department, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
FAU - Dibble, Brent
AU  - Dibble B
AD  - Emergency Department, Inova Fairfax Medical Campus, Falls Church, Virginia, USA.
FAU - Schultz, Brian
AU  - Schultz B
AD  - Department of Pediatric Emergency Medicine, Johns Hopkins Hospital, Baltimore, 
      Maryland, USA.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240222
PL  - United States
TA  - Acad Emerg Med
JT  - Academic emergency medicine : official journal of the Society for Academic 
      Emergency Medicine
JID - 9418450
SB  - IM
MH  - Humans
MH  - *Seizures/drug therapy
MH  - Electroencephalography/methods
MH  - *Status Epilepticus/drug therapy/epidemiology
MH  - Incidence
MH  - Retrospective Studies
OTO - NOTNLM
OT  - antiseizure medications
OT  - electroencephalography
OT  - seizures
EDAT- 2024/02/22 12:42
MHDA- 2024/03/14 06:47
CRDT- 2024/02/22 08:23
PHST- 2023/10/24 00:00 [revised]
PHST- 2023/09/08 00:00 [received]
PHST- 2023/11/01 00:00 [accepted]
PHST- 2024/03/14 06:47 [medline]
PHST- 2024/02/22 12:42 [pubmed]
PHST- 2024/02/22 08:23 [entrez]
AID - 10.1111/acem.14834 [doi]
PST - ppublish
SO  - Acad Emerg Med. 2024 Mar;31(3):249-255. doi: 10.1111/acem.14834. Epub 2024 Feb 
      22.