PMID- 38385776 OWN - NLM STAT- MEDLINE DCOM- 20240314 LR - 20240314 IS - 1433-7347 (Electronic) IS - 0942-2056 (Linking) VI - 32 IP - 3 DP - 2024 Mar TI - Derotational distal femoral osteotomy corrects excessive femoral anteversion in patients with patellofemoral instability: A systematic review. PG - 713-724 LID - 10.1002/ksa.12097 [doi] AB - PURPOSE: Patellofemoral instability (PFI) is a common condition that can be caused from multiple factors, including lower limb rotational malalignments. Determining precise criteria for performing corrective torsional osteotomy can be a daunting task due to the lack of consensus on normal and excessive values and the limited evidence-based data in the postoperative results. The purpose was to assess the clinical, functional and imaging outcomes following derotational distal femoral osteotomy (DDFO) in patients with PFI and/or anterior knee pain (AKP) associated with lower limb rotational malalignments. METHODS: Searches were conducted on PubMed, EMBASE and Web of Science databases up to October 2023. Studies reporting outcomes after DDFO in patients with PFI and/or AKP were eligible for the systematic review. The primary outcome was imaging metrics, especially femoral anteversion. Secondary outcomes included the patient-reported outcome measures (PROMs) (clinical and functional). Quantitative synthesis involved the use of weighted averages to calculate pre- to postoperative mean differences (MD) and compare them against the minimal clinically important difference (MCID). RESULTS: Ten studies (309 knees) were included with a mean follow-up of 36.1 +/- 11.7 months. Imaging outcomes consistently indicated the correction of femoral anteversion (MD = -19.4 degrees, 95% confidence interval: -20.1 to -18.7) following DDFO. PROMs showed significant improvements in most studies, exceeding the MCID. Patient satisfaction with the DDFO was high (93.3%). CONCLUSIONS: The DDFO was an effective treatment option for correcting excessive femoral anteversion in patients with PFI associated with clinically relevant functional and clinical improvement and a high satisfaction rate. LEVEL OF EVIDENCE: Level IV, systematic review of level II-IV studies. CI - (c) 2024 The Authors. Knee Surgery, Sports Traumatology, Arthroscopy published by John Wiley & Sons Ltd on behalf of European Society of Sports Traumatology, Knee Surgery and Arthroscopy. FAU - Ribeiro, Ricardo AU - Ribeiro R AD - School of Medicine, Minho University, Braga, Portugal. FAU - Gomes, Eluana AU - Gomes E AD - Clinica Espregueira-FIFA Medical Centre of Excellence, Porto, Portugal. FAU - Ferreira, Barbara AU - Ferreira B AD - School of Medicine, Minho University, Braga, Portugal. FAU - Figueiredo, Ines AU - Figueiredo I AD - School of Medicine, Minho University, Braga, Portugal. FAU - Valente, Cristina AU - Valente C AD - Clinica Espregueira-FIFA Medical Centre of Excellence, Porto, Portugal. AD - Dom Henrique Research Centre, Porto, Portugal. FAU - Delgado, Diego AU - Delgado D AD - Advanced Biological Therapy Unit, Hospital Vithas Vitoria, Vitoria-Gasteiz, Spain. FAU - Sanchez, Mikel AU - Sanchez M AD - Advanced Biological Therapy Unit, Hospital Vithas Vitoria, Vitoria-Gasteiz, Spain. AD - Arthroscopic Surgery Unit, Hospital Vithas Vitoria, Vitoria-Gasteiz, Spain. FAU - Andrade, Renato AU - Andrade R AD - Clinica Espregueira-FIFA Medical Centre of Excellence, Porto, Portugal. AD - Dom Henrique Research Centre, Porto, Portugal. AD - Porto Biomechanics Laboratory (LABIOMEP), Faculty of Sports, University of Porto, Porto, Portugal. FAU - Espregueira-Mendes, Joao AU - Espregueira-Mendes J AUID- ORCID: 0000-0001-7429-4900 AD - School of Medicine, Minho University, Braga, Portugal. AD - Clinica Espregueira-FIFA Medical Centre of Excellence, Porto, Portugal. AD - Dom Henrique Research Centre, Porto, Portugal. AD - ICVS/3B's-PT Government Associate Laboratory, Braga/Guimaraes, Portugal. AD - 3B's Research Group-Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Braga, Portugal. LA - eng PT - Journal Article PT - Systematic Review DEP - 20240222 PL - Germany TA - Knee Surg Sports Traumatol Arthrosc JT - Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA JID - 9314730 SB - IM MH - Humans MH - *Femur/surgery MH - Knee Joint/surgery MH - Treatment Outcome MH - Patient Satisfaction MH - Osteotomy/methods MH - Pain MH - *Patellofemoral Joint/surgery OTO - NOTNLM OT - anterior knee pain OT - derotational OT - distal femoral OT - osteotomy OT - patellofemoral instability EDAT- 2024/02/22 12:42 MHDA- 2024/03/14 06:47 CRDT- 2024/02/22 09:53 PHST- 2024/01/25 00:00 [revised] PHST- 2023/12/13 00:00 [received] PHST- 2024/02/04 00:00 [accepted] PHST- 2024/03/14 06:47 [medline] PHST- 2024/02/22 12:42 [pubmed] PHST- 2024/02/22 09:53 [entrez] AID - 10.1002/ksa.12097 [doi] PST - ppublish SO - Knee Surg Sports Traumatol Arthrosc. 2024 Mar;32(3):713-724. doi: 10.1002/ksa.12097. Epub 2024 Feb 22.