PMID- 38394099
OWN - NLM
STAT- MEDLINE
DCOM- 20240408
LR  - 20240408
IS  - 1601-5037 (Electronic)
IS  - 1601-5029 (Linking)
VI  - 22
IP  - 2
DP  - 2024 May
TI  - The impact of different states of type 2 diabetes when stratified by baseline 
      HbA1c on the periodontal outcomes of non-surgical periodontal treatment: A 
      systematic review and network meta-analysis.
PG  - 401-413
LID - 10.1111/idh.12789 [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) has been considered by many studies 
      to have a bidirectional relationship with periodontitis. This systematic review 
      and network meta-analysis aimed to investigate the impact of different states of 
      T2DM when stratified by baseline HbA1c on the clinical outcomes of non-surgical 
      periodontal treatment (NSPT). METHODS: This study followed the Preferred 
      Reporting Items for Meta-Analyses (PRISMA) guidelines and involved an electronic 
      literature search (from inception to the 2nd of January 2023). The study included 
      at least two groups of patients: chronic periodontitis only (No-DM) or 
      periodontitis and well-controlled/poorly controlled type 2 diabetes mellitus 
      (WC/PC-T2DM). Clinical outcomes included probing depth (PD) reduction, bleeding 
      on probing reduction, and clinical attachment level (CAL) gain. Direct and 
      indirect comparisons between groups were assessed by network meta-analysis, thus 
      allowing us to establish a treatment ranking. RESULTS: Ten prospective cohort 
      studies (11 data sets) were included for qualitative analysis and network 
      meta-analysis. The data included in this study had high consistency; in addition, 
      a funnel plot and Egger's test showed that the articles had low publication bias. 
      Network meta-analysis showed that the effect of NSPT in the No-DM group was 
      significantly better than the WC-T2DM group [weighted mean difference 
      (WMD) = 0.09, 95% confidence interval (CI) (0.01, 0.18)] and the PC-T2DM group 
      [WMD = 0.09, 95% CI (0.01, 0.18)] in terms of CAL gain and better than the 
      PC-T2DM group [WMD = 0.15, 95% CI (0.02, 0.28)] in terms of PD reduction. 
      According to the surface under the cumulative ranking value, the No-DM group had 
      the highest probability of achieving the best outcome following NSPT. 
      CONCLUSIONS: Collectively, our analyses show that T2DM exerts significant effects 
      on the outcomes of NSPT.
CI  - (c) 2024 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
FAU - Kang, Shuai
AU  - Kang S
AUID- ORCID: 0000-0003-3366-528X
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Liu, Zheng-Ya
AU  - Liu ZY
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Yuan, Huan-Huan
AU  - Yuan HH
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Wang, Shu-Min
AU  - Wang SM
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Pan, Ge-Ge
AU  - Pan GG
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Wei, Wei
AU  - Wei W
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
FAU - Jiang, Yi
AU  - Jiang Y
AD  - Institute of Stomatology, First Medical Center, Chinese People's Liberation Army 
      General Hospital, Beijing, China.
FAU - Hou, Yu
AU  - Hou Y
AD  - Institute of Stomatology, Chinese People's Liberation Army No.989 hospital, 
      Luoyang, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20240223
PL  - England
TA  - Int J Dent Hyg
JT  - International journal of dental hygiene
JID - 101168070
RN  - 0 (Glycated Hemoglobin)
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Dental Scaling
MH  - Glycated Hemoglobin
MH  - Network Meta-Analysis
MH  - Prospective Studies
MH  - *Chronic Periodontitis/therapy
OTO - NOTNLM
OT  - network meta-analysis
OT  - non-surgical periodontal treatment
OT  - systematic review
OT  - type 2 diabetes mellitus
EDAT- 2024/02/23 18:42
MHDA- 2024/04/08 06:44
CRDT- 2024/02/23 13:43
PHST- 2023/09/16 00:00 [revised]
PHST- 2023/07/15 00:00 [received]
PHST- 2024/02/11 00:00 [accepted]
PHST- 2024/04/08 06:44 [medline]
PHST- 2024/02/23 18:42 [pubmed]
PHST- 2024/02/23 13:43 [entrez]
AID - 10.1111/idh.12789 [doi]
PST - ppublish
SO  - Int J Dent Hyg. 2024 May;22(2):401-413. doi: 10.1111/idh.12789. Epub 2024 Feb 23.