PMID- 38399603
OWN - NLM
STAT- MEDLINE
DCOM- 20240226
LR  - 20240227
IS  - 1648-9144 (Electronic)
IS  - 1010-660X (Print)
IS  - 1010-660X (Linking)
VI  - 60
IP  - 2
DP  - 2024 Feb 12
TI  - Using Isolated Femoral Bifurcation Endarterectomy or Combined with Bypass Surgery 
      for Patients with Chronic Limb-Threatening Ischemia.
LID - 10.3390/medicina60020316 [doi]
LID - 316
AB  - Background and Objectives: The aim of this study was to evaluate the clinical 
      outcomes of patients suffering from chronic limb-threatening ischemia (CLTI) and 
      tissue loss treated with primary isolated femoral bifurcation endarterectomy 
      (FBE) or with FBE combined with bypass surgery. Materials and Methods: This 
      retrospective study was performed in a tertiary university-based care centre. 
      Between January 2008 and December 2019, a prospectively collected database of 
      patients suffering from CLTI and tissue loss and undergoing either primary FBE 
      (group A) or FBE in combination with bypass surgery (group B) was analysed. Study 
      endpoints were ulcer healing, primary and secondary patency rate, limb salvage, 
      and survival. Results: In total, FBE was performed in 73 patients and FBE with 
      bypass in 60 patients. Between both groups, there were no significant differences 
      regarding demographic data or the Global Limb Anatomic Staging System (GLASS) 
      grade III and IV of femoropopliteal lesions. After 3 years, ulcer healing could 
      be achieved in 72% of FBE and in 75% of FBE with bypass patients. The primary 
      patency rate was 95% and 91% for FBE and 83% and 80% for FBE with bypass after 
      one and three years, respectively. The 3-year limb-salvage rate was 78% for FBE 
      and 84% for FBE with bypass. The secondary patency rate after one and three years 
      was 99% and 97% for FBE and 93% and 88% for FBE with bypass. Conclusions: FBE and 
      FBE with bypass are equally effective for ulcer healing in cases of combined CFA 
      and superficial femoral artery lesions. There was no significant difference 
      between both groups regarding primary and secondary patency rates, limb salvage 
      rates and ulcer healing. Isolated FBE could be an alternative strategy in 
      patients with higher operative risk.
FAU - Ahmic, Edin
AU  - Ahmic E
AD  - Department of Cardiovascular and Endovascular Surgery, Paracelsus Medical 
      University Salzburg, Mullner Hauptstrasse 48, A-5020 Salzburg, Austria.
FAU - Hitzl, Wolfgang
AU  - Hitzl W
AUID- ORCID: 0000-0002-7696-1479
AD  - Research Office (Biostatistics), Paracelsus Medical University, Mullner 
      Hauptstrasse 48, A-5020 Salzburg, Austria.
FAU - Seitelberger, Rainald
AU  - Seitelberger R
AUID- ORCID: 0000-0002-1514-7190
AD  - Department of Cardiovascular and Endovascular Surgery, Paracelsus Medical 
      University Salzburg, Mullner Hauptstrasse 48, A-5020 Salzburg, Austria.
FAU - Linni, Klaus
AU  - Linni K
AD  - Department of Cardiovascular and Endovascular Surgery, Paracelsus Medical 
      University Salzburg, Mullner Hauptstrasse 48, A-5020 Salzburg, Austria.
LA  - eng
PT  - Journal Article
DEP - 20240212
PL  - Switzerland
TA  - Medicina (Kaunas)
JT  - Medicina (Kaunas, Lithuania)
JID - 9425208
SB  - IM
MH  - Humans
MH  - Chronic Limb-Threatening Ischemia
MH  - Retrospective Studies
MH  - Ulcer/etiology
MH  - Endarterectomy/adverse effects
MH  - *Vascular Grafting/adverse effects
MH  - Treatment Outcome
MH  - Vascular Patency
MH  - *Peripheral Arterial Disease/surgery
MH  - Risk Factors
PMC - PMC10890108
OTO - NOTNLM
OT  - bypass surgery
OT  - endarterectomy
OT  - femoral artery
OT  - lesion
COIS- The authors declare that there are no conflicts of interests.
EDAT- 2024/02/24 11:43
MHDA- 2024/02/26 06:45
PMCR- 2024/02/12
CRDT- 2024/02/24 01:20
PHST- 2024/01/08 00:00 [received]
PHST- 2024/01/30 00:00 [revised]
PHST- 2024/02/06 00:00 [accepted]
PHST- 2024/02/26 06:45 [medline]
PHST- 2024/02/24 11:43 [pubmed]
PHST- 2024/02/24 01:20 [entrez]
PHST- 2024/02/12 00:00 [pmc-release]
AID - medicina60020316 [pii]
AID - medicina-60-00316 [pii]
AID - 10.3390/medicina60020316 [doi]
PST - epublish
SO  - Medicina (Kaunas). 2024 Feb 12;60(2):316. doi: 10.3390/medicina60020316.