PMID- 38399929
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240227
IS  - 2073-4360 (Electronic)
IS  - 2073-4360 (Linking)
VI  - 16
IP  - 4
DP  - 2024 Feb 18
TI  - Lignocellulosic Membranes Grafted with N-Vinylcaprolactam Using Radiation 
      Chemistry: Load and Release Capacity of Vancomycin.
LID - 10.3390/polym16040551 [doi]
LID - 551
AB  - Radiation chemistry presents a unique avenue for developing innovative polymeric 
      materials with desirable properties, eliminating the need for chemical 
      initiators, which can be potentially detrimental, especially in sensitive sectors 
      like medicine. In this investigation, we employed a radiation-induced graft 
      polymerization process with N-vinylcaprolactam (NVCL) to modify lignocellulosic 
      membranes derived from Agave salmiana, commonly known as maguey. The membranes 
      underwent thorough characterization employing diverse techniques, including 
      contact angle measurement, degree of swelling, scanning electron microscopy 
      (SEM), atomic force microscopy (AFM), Fourier-transform infrared-attenuated total 
      reflectance spectroscopy (FTIR-ATR), nuclear magnetic resonance (CP-MAS 
      (13)C-NMR), X-ray photoelectron spectroscopy (XPS), and uniaxial tensile 
      mechanical tests. The membranes' ability to load and release an antimicrobial 
      glycopeptide drug was assessed, revealing significant enhancements in both drug 
      loading and sustained release. The grafting of PNVCL contributed to prolonged 
      sustained release by decreasing the drug release rate at temperatures above the 
      LCST. The release profiles were analyzed using the Higuchi, Peppas-Sahlin, and 
      Korsmeyer-Peppas models, suggesting a Fickian transport mechanism as indicated by 
      the Korsmeyer-Peppas model.
FAU - Renteria-Urquiza, Maite
AU  - Renteria-Urquiza M
AUID- ORCID: 0000-0002-4237-4196
AD  - Departamento de Quimica, Centro Universitario de Ciencias Exactas e Ingenierias, 
      Universidad de Guadalajara, Blvd. M. Garcia Barragan #1451, Guadalajara 44430, 
      Mexico.
FAU - Flores-Rojas, Guadalupe Gabriel
AU  - Flores-Rojas GG
AUID- ORCID: 0000-0003-1562-5217
AD  - Departamento de Quimica, Centro Universitario de Ciencias Exactas e Ingenierias, 
      Universidad de Guadalajara, Blvd. M. Garcia Barragan #1451, Guadalajara 44430, 
      Mexico.
AD  - Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias 
      Nucleares, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad 
      Universitaria, Mexico City 04510, Mexico.
AD  - Instituto de Investigaciones en Materiales, Universidad Nacional Autonoma de 
      Mexico, Mexico City 04510, Mexico.
FAU - Gomez-Lazaro, Belen
AU  - Gomez-Lazaro B
AD  - Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias 
      Nucleares, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad 
      Universitaria, Mexico City 04510, Mexico.
FAU - Lopez-Saucedo, Felipe
AU  - Lopez-Saucedo F
AUID- ORCID: 0000-0003-2806-0657
AD  - Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias 
      Nucleares, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad 
      Universitaria, Mexico City 04510, Mexico.
AD  - Facultad de Ciencias, Campus El Cerrillo Piedras Blancas, Universidad Autonoma 
      del Estado de Mexico, Carretera Toluca-Ixtlahuaca Km 15.5, Toluca 50200, Mexico.
FAU - Vera-Graziano, Ricardo
AU  - Vera-Graziano R
AUID- ORCID: 0000-0003-2870-9831
AD  - Instituto de Investigaciones en Materiales, Universidad Nacional Autonoma de 
      Mexico, Mexico City 04510, Mexico.
FAU - Mendizabal, Eduardo
AU  - Mendizabal E
AUID- ORCID: 0000-0003-4672-2052
AD  - Departamento de Quimica, Centro Universitario de Ciencias Exactas e Ingenierias, 
      Universidad de Guadalajara, Blvd. M. Garcia Barragan #1451, Guadalajara 44430, 
      Mexico.
FAU - Bucio, Emilio
AU  - Bucio E
AUID- ORCID: 0000-0003-4853-125X
AD  - Departamento de Quimica de Radiaciones y Radioquimica, Instituto de Ciencias 
      Nucleares, Universidad Nacional Autonoma de Mexico, Circuito Exterior, Ciudad 
      Universitaria, Mexico City 04510, Mexico.
LA  - eng
PT  - Journal Article
DEP - 20240218
PL  - Switzerland
TA  - Polymers (Basel)
JT  - Polymers
JID - 101545357
PMC - PMC10893404
OTO - NOTNLM
OT  - Agave salmiana
OT  - N-vynilcaprolactam
OT  - bio-membrane
OT  - biopolymer
OT  - cuticles
OT  - drug release
OT  - gamma rays
OT  - grafting
OT  - lignocellulose
OT  - membranes
OT  - skin maguey
OT  - thermal responsiveness
COIS- The authors declare no conflicts of interest.
EDAT- 2024/02/24 11:45
MHDA- 2024/02/24 11:46
PMCR- 2024/02/18
CRDT- 2024/02/24 01:22
PHST- 2024/01/12 00:00 [received]
PHST- 2024/02/09 00:00 [revised]
PHST- 2024/02/12 00:00 [accepted]
PHST- 2024/02/24 11:46 [medline]
PHST- 2024/02/24 11:45 [pubmed]
PHST- 2024/02/24 01:22 [entrez]
PHST- 2024/02/18 00:00 [pmc-release]
AID - polym16040551 [pii]
AID - polymers-16-00551 [pii]
AID - 10.3390/polym16040551 [doi]
PST - epublish
SO  - Polymers (Basel). 2024 Feb 18;16(4):551. doi: 10.3390/polym16040551.