PMID- 38402654 OWN - NLM STAT- MEDLINE DCOM- 20240320 LR - 20240411 IS - 1573-2509 (Electronic) IS - 0920-9964 (Linking) VI - 266 DP - 2024 Apr TI - Acculturation and clinical symptoms of schizophrenia among Latine adults in the United States. PG - 145-152 LID - S0920-9964(24)00057-4 [pii] LID - 10.1016/j.schres.2024.02.021 [doi] AB - BACKGROUND: Research on acculturation and schizophrenia spectrum disorders has yielded inconsistent findings. This study aimed to clarify the influence of acculturation on symptomatology in Latine individuals with schizophrenia in the United States. METHODS: The analysis involved cross-sectional data from Latine (n = 120) and non-Latine White (n = 60) adults with schizophrenia in San Diego, California. Participants completed the Short Acculturation Scale for Hispanics (SASH), Positive and Negative Symptom Scale, and Hamilton Depression Rating Scale in their preferred language. Univariate linear regressions were implemented to identify proxy measures as predictors of acculturation scores. Analyses of variance were conducted to analyze the relationship of SASH scores and proxy measures of acculturation to symptom severity. RESULTS: Latine participants presented more symptom severity than non-Latine Whites. When categorized by acculturation status (Spanish-preferring, bicultural, and English-preferring), Spanish-preferring participants presented similar psychiatric symptoms to the non-Latine group and less severe symptoms than both other Latine groups. Analyses identified study language as the strongest proxy measure for the SASH. Latine participants assessed in English had significantly worse positive and depressive symptoms than those assessed in Spanish. Nativity status moderated the relationship between study language and symptomatology. CONCLUSIONS: Findings support an association between acculturation and symptom severity among Latine individuals with schizophrenia. The use of proxy measures of acculturation may be useful in settings where time is constrained. Future research should continue to explore acculturation and symptomatology in Latine communities. CI - Copyright (c) 2024. Published by Elsevier B.V. FAU - Tibirica, Lize AU - Tibirica L AD - Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. FAU - Kohn, Jordan AU - Kohn J AD - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Herbert Wertheim School of Public Health and Human Longevity Science, University of California, San Diego, La Jolla, CA, USA. FAU - Patapoff, Molly AU - Patapoff M AD - Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. FAU - Williams, Allison P AU - Williams AP AD - Sam and Rose Stein Institute for Research on Aging, University of California, San Diego, La Jolla, CA, USA; Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA. FAU - Palmer, Barton W AU - Palmer BW AD - Department of Psychiatry, University of California, San Diego, La Jolla, CA, USA; Veterans Affairs San Diego Healthcare System, Mental Illness Research, Education, and Clinical Center (MIRECC), San Diego, CA, USA. FAU - Barrio, Concepcion AU - Barrio C AD - Suzanne Dworak-Peck School of Social Work, University of Southern California, Los Angeles, CA, USA. Electronic address: cbarrio@usc.edu. LA - eng GR - T32 MH019934/MH/NIMH NIH HHS/United States PT - Journal Article DEP - 20240224 PL - Netherlands TA - Schizophr Res JT - Schizophrenia research JID - 8804207 SB - IM MH - Adult MH - Humans MH - United States MH - *Schizophrenia/diagnosis MH - Acculturation MH - Hispanic or Latino/psychology MH - Cross-Sectional Studies MH - Language OTO - NOTNLM OT - Acculturation OT - Bicultural OT - Immigration OT - Latinx OT - Schizophrenia COIS- Declaration of competing interest The authors have no conflicts to disclose. EDAT- 2024/02/26 00:42 MHDA- 2024/03/20 06:46 CRDT- 2024/02/25 18:01 PHST- 2023/02/24 00:00 [received] PHST- 2023/10/05 00:00 [revised] PHST- 2024/02/17 00:00 [accepted] PHST- 2024/03/20 06:46 [medline] PHST- 2024/02/26 00:42 [pubmed] PHST- 2024/02/25 18:01 [entrez] AID - S0920-9964(24)00057-4 [pii] AID - 10.1016/j.schres.2024.02.021 [doi] PST - ppublish SO - Schizophr Res. 2024 Apr;266:145-152. doi: 10.1016/j.schres.2024.02.021. Epub 2024 Feb 24.