PMID- 38404086
OWN - NLM
STAT- MEDLINE
DCOM- 20240227
LR  - 20240227
IS  - 1819-2718 (Electronic)
IS  - 1025-9589 (Linking)
VI  - 35
IP  - 3
DP  - 2023 Jul-Sep
TI  - Non-Obstructive Coronaries In Patients Presenting With The Non St-Elevation Acute 
      Coronary Syndrome.
PG  - 428-432
LID - 10.55519/JAMC-03-12028 [doi]
AB  - BACKGROUND: Worldwide, cardiovascular diseases are the major cause of mortality 
      and morbidity with acute coronary syndrome as the most common clinical 
      manifestation. In a typical clinical setup, around 30% of the patients presented 
      with "ST-segment elevation myocardial infarction (STEMI)" caused by the complete 
      occlusion of the coronary artery and the remaining 70% with intermittent or 
      partial occlusion of the coronary termed as non-ST elevation The aim of this 
      study was to assess the prevalence and characteristics of non-obstructive 
      coronary arteries among patients presenting with non ST-elevation acute coronary 
      syndrome (NSTE-ACS) at a tertiary care cardiac center of Karachi, Pakistan. 
      METHODS: This was a descriptive cross-sectional study, conducted at a tertiary 
      care hospital in Karachi. Study inclusion criteria were patients of either gender 
      admitted with NSTE-ACS and aged between 30-70 years. A routine coronary angiogram 
      was performed in all the patients and the absence of >/=50% stenosis in any major 
      epicardial vessel was taken in non-obstructive coronaries. RESULTS: A total of 
      174 patients (30-70 years) were included, of which 99 (56.9%) were male and the 
      mean age was 59.43+/-11.24 years. In the distribution of socioeconomic status, 54 
      (31.0%) were lower class, middle class 81 (46.6%) while upper-class status were 
      39 (22.4%). Hypertension was observed in 76 (43.7%), chronic kidney disease in 20 
      (11.5%), and hyperlipidemia in 55 (31.6%). Non-obstructive coronary arteries were 
      noted in 25 (14.4%) patients. CONCLUSIONS: It is to be concluded that 
      non-obstructive coronary arteries are fairly prevalent in patients arriving in 
      hospitals with NSTE-ACS in our population. Further research is needed to better 
      understand the underlying pathophysiology and optimal management strategies for 
      patients with NOCA in the setting of NSTEMI.
FAU - Zada, Shakir
AU  - Zada S
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
FAU - Bhatti, Khalid Iqbal
AU  - Bhatti KI
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
FAU - Zeb, Muhammad
AU  - Zeb M
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
FAU - Pirah, Romana
AU  - Pirah R
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
FAU - Musaddiq, Daniyal
AU  - Musaddiq D
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
FAU - Memon, Aziz Ur Rehman
AU  - Memon AUR
AD  - National Institute of Cardiovascular Diseases (NICVD), Karachi, Pakistan.
LA  - eng
PT  - Journal Article
PL  - Pakistan
TA  - J Ayub Med Coll Abbottabad
JT  - Journal of Ayub Medical College, Abbottabad : JAMC
JID - 8910750
SB  - IM
MH  - Humans
MH  - Male
MH  - Adult
MH  - Middle Aged
MH  - Aged
MH  - Female
MH  - *Acute Coronary Syndrome/epidemiology
MH  - Cross-Sectional Studies
MH  - Risk Assessment
MH  - *Non-ST Elevated Myocardial Infarction/epidemiology
MH  - *Hypertension
MH  - *Percutaneous Coronary Intervention
OTO - NOTNLM
OT  - Acute Coronary Syndrome; CAB; Non-Obstructive Coronaries; NSTEMI; PCI
EDAT- 2024/02/26 06:42
MHDA- 2024/02/27 06:45
CRDT- 2024/02/26 02:03
PHST- 2024/02/27 06:45 [medline]
PHST- 2024/02/26 06:42 [pubmed]
PHST- 2024/02/26 02:03 [entrez]
AID - 12028/3563 [pii]
AID - 10.55519/JAMC-03-12028 [doi]
PST - ppublish
SO  - J Ayub Med Coll Abbottabad. 2023 Jul-Sep;35(3):428-432. doi: 
      10.55519/JAMC-03-12028.