PMID- 38412241 OWN - NLM STAT- MEDLINE DCOM- 20240418 LR - 20240418 IS - 1466-447X (Electronic) IS - 0264-0414 (Linking) VI - 42 IP - 1 DP - 2024 Jan TI - Blood flow restriction augments exercise-induced pressure pain thresholds over repetition and effort matched conditions. PG - 73-84 LID - 10.1080/02640414.2024.2321012 [doi] AB - We sought to determine the effects of blood flow restriction (BFR) on exercise-induced hypoalgesia, specifically using low-load (LL) resistance exercise (30% 1RM) protocols that accounted for each individual's local muscular endurance capabilities. Forty-four participants completed four conditions: (1) 70% of maximal BFR repetitions with blood flow restriction (LL+BFR exercise); (2) 70% maximal BFR repetitions without LL+BFR (LL exercise); (3) 70% maximal free flow repetitions (LL+EFFORT exercise); (4) time-matched, non-exercise control (CON). Pressure pain threshold (PPT) was measured before and after exercise. Ischaemic pain threshold and tolerance was assessed only at post. The change in upper body PPT was greater for LL+BFR exercise compared to LL exercise [difference of 0.15 (0.35) kg/cm(2)], LL+EFFORT exercise [difference of 0.23 (0.45) kg/cm(2)], and the CON condition. The change in lower body PPT was greater for LL+BFR exercise compared to LL exercise [difference of 0.40 (0.55) kg/cm(2)], LL+EFFORT exercise [difference of 0.36 (0.62) kg/cm(2)], and the CON condition. Ischaemic pain thresholds and tolerances did not change. Submaximal exercise with BFR resulted in systemic increases in PPT but had no influence on ischaemic pain sensitivity. This effect is likely unique to BFR as we did not see changes in the effort matched free flow condition. FAU - Hammert, William B AU - Hammert WB AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Song, Jun Seob AU - Song JS AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Yamada, Yujiro AU - Yamada Y AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Kataoka, Ryo AU - Kataoka R AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Wong, Vickie AU - Wong V AD - Health and Exercise Science, Solent University, Southampton, UK. FAU - Spitz, Robert W AU - Spitz RW AD - Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA. FAU - Seffrin, Aldo AU - Seffrin A AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Kang, Anna AU - Kang A AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. FAU - Loenneke, Jeremy P AU - Loenneke JP AUID- ORCID: 0000-0001-5409-9075 AD - Department of Health, Exercise Science and Recreation Management. Kevser Ermin Applied Physiology Laboratory, The University of Mississippi, University, MS, USA. LA - eng PT - Journal Article DEP - 20240227 PL - England TA - J Sports Sci JT - Journal of sports sciences JID - 8405364 SB - IM MH - Humans MH - *Pain Threshold MH - Regional Blood Flow/physiology MH - Hemodynamics MH - Pain MH - Exercise/physiology MH - *Resistance Training/methods MH - Muscle, Skeletal/physiology OTO - NOTNLM OT - Blood flow restriction OT - pain sensitivity OT - pain tolerance OT - resistance exercise OT - submaximal exercise EDAT- 2024/02/27 18:42 MHDA- 2024/04/18 06:44 CRDT- 2024/02/27 14:52 PHST- 2024/04/18 06:44 [medline] PHST- 2024/02/27 18:42 [pubmed] PHST- 2024/02/27 14:52 [entrez] AID - 10.1080/02640414.2024.2321012 [doi] PST - ppublish SO - J Sports Sci. 2024 Jan;42(1):73-84. doi: 10.1080/02640414.2024.2321012. Epub 2024 Feb 27.