PMID- 38420158
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240301
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 12
IP  - 2
DP  - 2024 Feb
TI  - Comparison of diagnostic outcomes, safety, and cost of Franseen-tip 19G versus 
      22G needles for endoscopic ultrasound-guided liver biopsies.
PG  - E291-E296
LID - 10.1055/a-2226-1337 [doi]
AB  - Background and study aims Favorable outcomes were noted with refinement in newer 
      endoscopic ultrasound-guided liver biopsy (EUS-LB) needle tips. Still, the 
      overall usefulness and benefit are yet to be well explored. Patients and methods 
      This was a retrospective analysis of patients with EUS-LB (Franseen-tip 19G 
      versus 22G FNB needle) over 2 years. EUS-LB was obtained in a one-pass, 
      two-actuation, modified wet suction technique. Diagnostic yield, fragmentation 
      rate, aggregate specimen length (AL), number of complete portal tracts (CPT), 
      length of longest intact core (LIC), adverse events (AEs) (early), and cost of 
      the procedure (1USD = 82 INR) were compared. Results Fifty-four patients (33 
      [61.1%], female) successfully underwent EUS-LB with a median age of 46 years 
      (interquartile range [IQR] 34-54); the majority 32 (59.2%) underwent 19G 
      biopsies. There was a significantly increased median (IQR) AL in the 19G compared 
      with 22G (20 mm [19-21] vs. 15 [14-15], P < 0.001), respectively. Similarly, 
      significantly lengthier median LIC and CPT were seen, respectively. A 
      nonsignificant diagnostic yield was noted (100% vs. 90.9%, P = 0.082), 
      respectively. The fragmentation rate was higher in 22G FNB needles (36.4% [95% CI 
      16-56] vs. 12.5% [95% CI 1-24], respectively; P = 0.038). Seven patients (12.9%) 
      had mild AEs with no difference between groups. The average procedure cost with 
      19G was INR 63000 (768$), and with 22G needle was INR 54500 (664$). Conclusions 
      The Franseen-tip 19G outperforms 22G with a significantly lower fragmentation 
      rate, longer AL, LIC, and a higher number of CPT with a marginal increase in the 
      procedure cost, without any difference in diagnostic yield and safety.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial-License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commercial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Dalal, Ankit
AU  - Dalal A
AUID- ORCID: 0000-0001-5729-8897
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Kamat, Nagesh
AU  - Kamat N
AUID- ORCID: 0000-0003-3504-7290
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Patil, Gaurav
AU  - Patil G
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Vadgaonkar, Amol
AU  - Vadgaonkar A
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Parekh, Sanil
AU  - Parekh S
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Vora, Sehajad
AU  - Vora S
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
FAU - Maydeo, Amit
AU  - Maydeo A
AUID- ORCID: 0000-0003-1687-4936
AD  - Institute of Gastrosciences, Sir HN Reliance Foundation Hospital and Research 
      Centre, Mumbai, India. RINGGOLD: 81727
LA  - eng
PT  - Journal Article
DEP - 20240228
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC10901641
OTO - NOTNLM
OT  - Endoscopic ultrasonography
OT  - Fine-needle aspiration/biopsy
OT  - Intervention EUS
COIS- Conflict of Interest The authors declare that they have no conflict of interest.
EDAT- 2024/02/29 06:42
MHDA- 2024/02/29 06:43
PMCR- 2024/02/01
CRDT- 2024/02/29 04:09
PHST- 2023/09/14 00:00 [received]
PHST- 2023/12/01 00:00 [accepted]
PHST- 2024/02/29 06:43 [medline]
PHST- 2024/02/29 06:42 [pubmed]
PHST- 2024/02/29 04:09 [entrez]
PHST- 2024/02/01 00:00 [pmc-release]
AID - EIO-2023-09-3138-OA [pii]
AID - 10.1055/a-2226-1337 [doi]
PST - epublish
SO  - Endosc Int Open. 2024 Feb 28;12(2):E291-E296. doi: 10.1055/a-2226-1337. 
      eCollection 2024 Feb.