PMID- 38422884
OWN - NLM
STAT- MEDLINE
DCOM- 20240311
LR  - 20240311
IS  - 1872-6976 (Electronic)
IS  - 0167-4943 (Linking)
VI  - 120
DP  - 2024 May
TI  - Adverse outcomes of intrinsic capacity in older adults: A scoping review.
PG  - 105335
LID - S0167-4943(24)00011-6 [pii]
LID - 10.1016/j.archger.2024.105335 [doi]
AB  - Background and Purpose Intrinsic capacity (IC) has been shown to have the 
      greatest impact on an individual's health status and health trajectory and can 
      independently predict adverse outcomes such as mortality and care dependency in 
      older adults. However, the current understanding of adverse outcomes associated 
      with IC is incomplete. Methods A scoping review of the literature from PubMed, 
      Web of Science (WOS), The Cochrane Library, CINAHL, and Embase databases was 
      conducted from January 2015 to March 2023 to identify articles related to the 
      adverse outcomes associated with IC in older adults. Results 711 studies met 
      screening criteria, and 25 studies met inclusion criteria. These studies reported 
      a total of 17 adverse outcomes related to IC across four domains. (1) Adverse 
      outcomes in the physiological function domains included frailty, pneumonia onset, 
      memory impairment, polypharmacy, incontinence, and poor/fair self-rated health. 
      (2) Clinical outcomes domains included IADL disability, ADL disability, 
      mortality, falls, autonomy decline, and incident dependence. (3) The resource 
      utilization domains included hospitalization, nursing home stays, polypharmacy 
      healthcare costs, and emergency department visits. (4) The other domains mainly 
      included poor quality of life. Conclusion It is evident that IC decline in older 
      adults is associated with a broad spectrum of adverse outcomes spanning cognitive 
      function, activity ability, sensory perception, physical and mental health and 
      living standards. Future studies should further deepen the exploration of IC.
CI  - Copyright (c) 2024 Elsevier B.V. All rights reserved.
FAU - Yang, Yiyi
AU  - Yang Y
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: 1044928133@qq.com.
FAU - Ma, Guifen
AU  - Ma G
AD  - Gannan Tibetan Autonomous Prefecture health school, Gannan Tibetan Autonomous 
      Prefecture, China. Electronic address: mgf19832005@126.com.
FAU - Wei, Suhong
AU  - Wei S
AD  - Department of Endocrinology, Gansu Provincial People's Hospital, Lanzhou, China. 
      Electronic address: gansu19820208@163.com.
FAU - Wei, Xiaoqin
AU  - Wei X
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: weixq145@163.com.
FAU - Yan, Bailing
AU  - Yan B
AD  - ICU, the First Hospital of Lanzhou University, Lanzhou, China. Electronic 
      address: 2834631738@qq.com.
FAU - Yuan, Yue
AU  - Yuan Y
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: 2980821526@qq.com.
FAU - Chen, Yajing
AU  - Chen Y
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: 1144979085@qq.com.
FAU - Qin, Jiangxia
AU  - Qin J
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: 1973924850@qq.com.
FAU - Ma, Yuxia
AU  - Ma Y
AD  - Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, 
      China. Electronic address: yuxiama@lzu.edu.cn.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240117
PL  - Netherlands
TA  - Arch Gerontol Geriatr
JT  - Archives of gerontology and geriatrics
JID - 8214379
SB  - IM
MH  - Humans
MH  - Aged
MH  - Quality of Life
MH  - Health Status
MH  - *Frailty
MH  - *Disabled Persons
MH  - Polypharmacy
OTO - NOTNLM
OT  - Adverse outcome
OT  - Disability
OT  - Healthy aging
OT  - Intrinsic capacity
OT  - Older adults
COIS- Declaration of competing interest The Authors declare that there is no conflict 
      of interest.
EDAT- 2024/03/01 01:22
MHDA- 2024/03/11 06:44
CRDT- 2024/02/29 18:14
PHST- 2023/11/17 00:00 [received]
PHST- 2024/01/13 00:00 [revised]
PHST- 2024/01/15 00:00 [accepted]
PHST- 2024/03/11 06:44 [medline]
PHST- 2024/03/01 01:22 [pubmed]
PHST- 2024/02/29 18:14 [entrez]
AID - S0167-4943(24)00011-6 [pii]
AID - 10.1016/j.archger.2024.105335 [doi]
PST - ppublish
SO  - Arch Gerontol Geriatr. 2024 May;120:105335. doi: 10.1016/j.archger.2024.105335. 
      Epub 2024 Jan 17.