PMID- 38424145
OWN - NLM
STAT- MEDLINE
DCOM- 20240304
LR  - 20240304
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 14
IP  - 1
DP  - 2024 Feb 29
TI  - Predictors of microvascular complications in patients with type 2 diabetes 
      mellitus at regional referral hospitals in the central zone, Tanzania: a 
      cross-sectional study.
PG  - 5035
LID - 10.1038/s41598-024-55556-x [doi]
LID - 5035
AB  - Microvascular complications encompass a group of diseases which result from 
      long-standing chronic effect of diabetes mellitus (DM). We aimed to determine the 
      prevalence of microvascular complications and associated risk factors among 
      patients with type 2 diabetes mellitus (T2DM). A cross-sectional analytical 
      hospital-based study was conducted at Singida and Dodoma regional referral 
      hospitals in Tanzania from December 2021 to September 2022. A total of 422 
      patients with T2DM were included in the analysis by determining the prevalence of 
      microvascular complications and their predictors using multivariable logistic 
      regression analysis. A two-tailed p value less than 0.05 was considered 
      statistically significant. The prevalence of microvascular complications was 
      57.6% (n = 243) and diabetic retinopathy was the most common microvascular 
      complication which accounted for 21.1% (n = 89). Having irregular physical 
      activity (AOR = 7.27, 95% CI = 2.98-17.71, p < 0.001), never having physical 
      activity (AOR = 2.38, 95% CI = 1.4-4.01, p = 0.013), being hypertensive 
      (AOR = 5.0, 95% CI = 2.14-11.68, p = 0.030), having T2DM for more than 5 years 
      (AOR = 2.74, 95% CI = 1.42-5.26, p = 0.025), being obese (AOR = 2.63, 95% CI = 
      1.22-5.68, p = 0.010), and taking anti-diabetic drugs irregularly (AOR = 1.94, 
      95% CI = 0.15-0.77, p < 0.001) were the predictors of microvascular 
      complications. This study has revealed a significant proportion of microvascular 
      complications in a cohort of patients with T2DM. Lack of regular physical 
      activity, being obese, taking anti-diabetic drugs irregularly, presence of 
      hypertension, and long-standing duration of the disease, were significantly 
      associated with microvascular complications.
CI  - (c) 2024. The Author(s).
FAU - Shillah, Wilfred B
AU  - Shillah WB
AD  - Department of Community Medicine, School of Medicine and Dentistry, University of 
      Dodoma, Dodoma, Tanzania.
FAU - Yahaya, James J
AU  - Yahaya JJ
AD  - Department of Pathology, School of Health Sciences, Soroti University, P. O. Box 
      211, Soroti, Uganda. Email-jayame76@gmail.com.
FAU - Morgan, Emmanuel D
AU  - Morgan ED
AD  - Department of Pathology, School of Health Sciences, Soroti University, P. O. Box 
      211, Soroti, Uganda.
FAU - Bintabara, Deogratius
AU  - Bintabara D
AD  - Department of Community Medicine, School of Medicine and Dentistry, University of 
      Dodoma, Dodoma, Tanzania.
LA  - eng
PT  - Journal Article
DEP - 20240229
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Cross-Sectional Studies
MH  - Tanzania/epidemiology
MH  - Obesity/complications
MH  - *Hypertension/complications/epidemiology
MH  - Hospitals
MH  - Referral and Consultation
PMC - PMC10904798
OTO - NOTNLM
OT  - Microvascular complications
OT  - Predictors
OT  - Type 2 diabetes mellitus
COIS- The authors declare no competing interests.
EDAT- 2024/03/01 01:27
MHDA- 2024/03/04 06:45
PMCR- 2024/02/29
CRDT- 2024/02/29 23:21
PHST- 2023/10/29 00:00 [received]
PHST- 2024/02/25 00:00 [accepted]
PHST- 2024/03/04 06:45 [medline]
PHST- 2024/03/01 01:27 [pubmed]
PHST- 2024/02/29 23:21 [entrez]
PHST- 2024/02/29 00:00 [pmc-release]
AID - 10.1038/s41598-024-55556-x [pii]
AID - 55556 [pii]
AID - 10.1038/s41598-024-55556-x [doi]
PST - epublish
SO  - Sci Rep. 2024 Feb 29;14(1):5035. doi: 10.1038/s41598-024-55556-x.