PMID- 38424686
OWN - NLM
STAT- MEDLINE
DCOM- 20240304
LR  - 20240321
IS  - 2054-1058 (Electronic)
IS  - 2054-1058 (Linking)
VI  - 11
IP  - 3
DP  - 2024 Mar
TI  - Prevalence, factors and early outcomes of frailty among hospitalized older 
      patients with valvular heart disease: A prospective observational cohort study.
PG  - e2122
LID - 10.1002/nop2.2122 [doi]
LID - e2122
AB  - AIM: The aim was to investigate the prevalence of, and factors related to 
      frailty, together with early clinical outcomes, in hospitalized older patients 
      with valvular heart disease (VHD) in China. DESIGN: A prospective observational 
      cohort study was conducted. METHODS: A validated prospective survey was conducted 
      to assess the prevalence of frailty, factors associated with it, and early 
      clinical outcomes in hospitalized older patients with VHD, utilizing Fried's 
      criterion. A total of 207 consecutive participants aged 65 years and older who 
      underwent cardiac surgery were included in the study, spanning from September 
      2021 to December 2021. RESULTS: Frailty was detected in 78 patients (37.7%). 
      Patients with multimorbidity, a New York Heart Association (NYHA) class of 
      III/IV, or masticatory dysfunction had a greater incidence of frailty (p < 0.05). 
      Patients with a normal albumin level and a higher frequency of exercise had a 
      lower incidence of frailty (p < 0.05). Patients with frailty had longer hospital 
      and intensive care unit stays and greater hospitalization costs than did those 
      without frailty (p < 0.05). The 30-day adverse event rate of the frail group was 
      also greater (11.5% vs. 3.1%). Therefore, early screening for conditions such as 
      multimorbidity, cardiac dysfunction, and hypoalbuminemia is urgently needed to 
      effectively address frailty, as it has been linked to unfavourable early 
      outcomes. Moreover, promoting exercise and improving masticatory function and 
      nutrition are crucial for preventing and managing frailty in older patients with 
      VHD.
CI  - (c) 2024 The Authors. Nursing Open published by John Wiley & Sons Ltd.
FAU - Shen, Zhiyun
AU  - Shen Z
AD  - Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Zhang, Yuan
AU  - Zhang Y
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Zhou, Daxin
AU  - Zhou D
AD  - Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Lv, Jiaying
AU  - Lv J
AD  - Analytics, Novartis China, Shanghai, China.
FAU - Huang, Chenxu
AU  - Huang C
AD  - Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Chen, Yihong
AU  - Chen Y
AD  - Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Zhang, Yuxia
AU  - Zhang Y
AUID- ORCID: 0000-0003-4419-7004
AD  - Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.
FAU - Lin, Ying
AU  - Lin Y
AUID- ORCID: 0000-0002-0943-2606
AD  - Department of Nursing, Zhongshan Hospital, Fudan University, Shanghai, China.
LA  - eng
GR  - 2022ZSQN07/Youth Fund of Zhongshan Hospital, Fudan University/
GR  - 2020YFC2008100/The National Key R&D Program of China/
GR  - xk-082-011/The Cardiovascular Disease Nursing Program of Zhongshan Hospital, 
      Fudan University/
GR  - FNF201935/Fuxing Nursing Research Fund of Fudan University/
PT  - Journal Article
PT  - Observational Study
PL  - United States
TA  - Nurs Open
JT  - Nursing open
JID - 101675107
SB  - IM
MH  - Aged
MH  - Humans
MH  - *Frailty/epidemiology/complications/diagnosis
MH  - Frail Elderly
MH  - Prospective Studies
MH  - Prevalence
MH  - *Heart Valve Diseases/epidemiology/surgery/complications
PMC - PMC10904767
OTO - NOTNLM
OT  - early outcomes
OT  - factors
OT  - frailty
OT  - frailty phenotype
OT  - valvular heart disease
COIS- On behalf of all authors, the corresponding author states that there are no 
      conflicts of interest.
EDAT- 2024/03/01 06:44
MHDA- 2024/03/04 06:46
PMCR- 2024/02/29
CRDT- 2024/03/01 00:23
PHST- 2023/12/18 00:00 [revised]
PHST- 2023/06/06 00:00 [received]
PHST- 2024/02/07 00:00 [accepted]
PHST- 2024/03/04 06:46 [medline]
PHST- 2024/03/01 06:44 [pubmed]
PHST- 2024/03/01 00:23 [entrez]
PHST- 2024/02/29 00:00 [pmc-release]
AID - NOP22122 [pii]
AID - 10.1002/nop2.2122 [doi]
PST - ppublish
SO  - Nurs Open. 2024 Mar;11(3):e2122. doi: 10.1002/nop2.2122.