PMID- 38426120 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240302 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 11 DP - 2024 TI - Case Report: Resuscitation of patient with tumor-induced acute pulmonary embolism by venoarterial extracorporeal membrane oxygenation. PG - 1322387 LID - 10.3389/fcvm.2024.1322387 [doi] LID - 1322387 AB - BACKGROUND: Pulmonary embolism is a condition of right cardiac dysfunction due to pulmonary circulation obstruction. Malignant tumor-induced pulmonary embolism, which has a poor therapeutic outcome and a significant impact on hemodynamics, is the cause of sudden death in patients with malignant tumors. CASE DESCRIPTION: A 38-year-old female patient, who had a medical history of right renal hamartoma, and right renal space-occupying lesion, was admitted to the hospital. During the procedure to resect the right renal malignancy, the blood pressure and end-tidal carbon dioxide level dropped, and a potential pulmonary embolism was considered as a possibility. After inferior vena cava embolectomy, the hemodynamics in the patient remained unstable. The successful establishment of venoarterial extracorporeal membrane oxygenation (VA-ECMO) resulted in the stabilization of her hemodynamics and ventilation. On Day 2 of VA-ECMO support, her respiration and hemodynamics were relatively stable, and ECMO assistance was successfully terminated following the "pump-controlled retrograde trial off (PCRTO)" test on Day 6. The patient improved gradually after the procedure and was discharged from the hospital after 22 days. CONCLUSION: VA-ECMO can be used as a transitional resuscitation technique for patients with massive pulmonary embolism. It is critical for the perfusion of vital organs and can assist with surgical or interventional treatment, lower right heart pressure, and hemodynamic stability. VA-ECMO has a significant impact on patient prognosis and can reduce the mortality rate. CI - (c) 2024 Zhang, Zhang, Li, Guo, Qi, Xing and Wang. FAU - Zhang, Shuang-Long AU - Zhang SL AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. AD - Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China. FAU - Zhang, Qi-Feng AU - Zhang QF AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. FAU - Li, Gang AU - Li G AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. FAU - Guo, Miao AU - Guo M AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. FAU - Qi, Xiao-Xia AU - Qi XX AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. FAU - Xing, Xiao-Hui AU - Xing XH AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. FAU - Wang, Zheng AU - Wang Z AD - Department of Critical Care Medicine, Peking University International Hospital, Beijing, China. LA - eng PT - Case Reports DEP - 20240215 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 PMC - PMC10902156 OTO - NOTNLM OT - VA-ECMO OT - pulmonary embolism OT - renal cell carcinoma OT - resuscitation OT - tumor-induced pulmonary COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2024/03/01 06:44 MHDA- 2024/03/01 06:45 PMCR- 2024/01/01 CRDT- 2024/03/01 03:58 PHST- 2023/10/16 00:00 [received] PHST- 2024/01/09 00:00 [accepted] PHST- 2024/03/01 06:45 [medline] PHST- 2024/03/01 06:44 [pubmed] PHST- 2024/03/01 03:58 [entrez] PHST- 2024/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2024.1322387 [doi] PST - epublish SO - Front Cardiovasc Med. 2024 Feb 15;11:1322387. doi: 10.3389/fcvm.2024.1322387. eCollection 2024.