PMID- 38430233
OWN - NLM
STAT- Publisher
LR  - 20240302
IS  - 1434-3916 (Electronic)
IS  - 0936-8051 (Linking)
DP  - 2024 Mar 2
TI  - High survivorship rate and good clinical outcomes after high tibial osteotomy in 
      patients with radiological advanced medial knee osteoarthritis: a systematic 
      review.
LID - 10.1007/s00402-024-05254-0 [doi]
AB  - INTRODUCTION: The role of valgus producing high tibial osteotomy (HTO) for the 
      treatment of advanced knee osteoarthritis (OA) is still controversial. The aim of 
      the current systematic review was to assess survivorship and patient-reported 
      outcomes (PROMs) of high tibial osteotomy in patients with radiological advanced 
      medial knee OA. METHODS: A systematic search of PubMed, Cochrane and EMBASE 
      database was performed in July 2023 in accordance with the Preferred Reporting 
      Items for Systematic reviews and Meta-Analysis (PRISMA) guidelines. Inclusion and 
      exclusion criteria were applied to identify studies investigating the 
      survivorship rate and PROMs of valgus-producing high tibial osteotomy in patients 
      with advanced knee OA at x-ray assessment in the medial compartment at 
      minimum-two-years follow up. Advanced radiological OA was defined as Kellgren 
      Lawrence (K-L) >/= 3 or Ahlbach >/= 2. Survivorship was defined as percentage of 
      patients free of total knee arthroplasty (TKA) at follow-up. Clinical 
      interpretation of provided PROMs were performed according to minimal clinically 
      important difference (MCID) and patient acceptable symptom state (PASS) target 
      values reported in literature. Survivorship data and PROMs scores were extracted, 
      and studies were stratified based on selected study features. The quality of 
      included studies was assessed with modified Coleman score. RESULTS: A total of 18 
      studies, totalling 1296 knees with a mean age between 46.9 and 67 years old, were 
      included. Average survivorship was of 74.6% (range 60 - 98.1%) at 10-years follow 
      up. The subjective scoring systems showed good results according to MCID and 
      PASS, and postoperative improvements were partially maintained until final 
      follow-up. CONCLUSION: HTO is worth considering as treatment choice even in 
      patients affected by radiological advanced medial knee osteoarthritis. Long term 
      survivorship and good patient reported clinical outcomes could be expected in 
      this population. LEVEL OF EVIDENCE: IV; systematic review of level III-IV 
      studies.
CI  - (c) 2024. The Author(s).
FAU - Dal Fabbro, Giacomo
AU  - Dal Fabbro G
AUID- ORCID: 0000-0002-8258-6425
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy. giacomo.dalfabbro@studio.unibo.it.
AD  - Universita di Bologna, Dipartimento di Scienze Biomediche e Neuromotorie DIBINEM, 
      Bologna, Italy. giacomo.dalfabbro@studio.unibo.it.
FAU - Grassi, Alberto
AU  - Grassi A
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
FAU - Agostinone, Piero
AU  - Agostinone P
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
FAU - Lucidi, Gian Andrea
AU  - Lucidi GA
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
FAU - Fajury, Raschid
AU  - Fajury R
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
FAU - Ravindra, Abhijit
AU  - Ravindra A
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
FAU - Zaffagnini, Stefano
AU  - Zaffagnini S
AD  - II Clinica Ortopedica e Traumatologica, IRCCS Istituto Ortopedico Rizzoli, Via G. 
      C. Pupilli 1, Bologna, 40136, Italy.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240302
PL  - Germany
TA  - Arch Orthop Trauma Surg
JT  - Archives of orthopaedic and trauma surgery
JID - 9011043
SB  - IM
OTO - NOTNLM
OT  - Advanced osteoarthritis
OT  - Bone-on-bone
OT  - HTO
OT  - High tibial osteotomy
OT  - PROMs
OT  - Survivorship
EDAT- 2024/03/02 12:47
MHDA- 2024/03/02 12:47
CRDT- 2024/03/02 11:03
PHST- 2023/09/01 00:00 [received]
PHST- 2024/02/17 00:00 [accepted]
PHST- 2024/03/02 12:47 [medline]
PHST- 2024/03/02 12:47 [pubmed]
PHST- 2024/03/02 11:03 [entrez]
AID - 10.1007/s00402-024-05254-0 [pii]
AID - 10.1007/s00402-024-05254-0 [doi]
PST - aheadofprint
SO  - Arch Orthop Trauma Surg. 2024 Mar 2. doi: 10.1007/s00402-024-05254-0.