PMID- 38433240
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240306
IS  - 2326-0254 (Print)
IS  - 2326-0254 (Electronic)
IS  - 2326-0254 (Linking)
VI  - 11
IP  - 1
DP  - 2024 Mar 4
TI  - Evaluation of a new dynamic real-time visualization 25 kHz swept-source optical 
      coherence tomography based biometer.
PG  - 9
LID - 10.1186/s40662-024-00377-2 [doi]
LID - 9
AB  - BACKGROUND: To evaluate the intraobserver repeatability and interobserver 
      reproducibility of a newly developed dynamic real-time visualization 25 kHz 
      swept-source optical coherence tomography (SS-OCT) based biometer (ZW-30, 
      TowardPi Medical Technology Ltd, China) and compare its agreement with another 
      SS-OCT based biometer (IOLMaster 700, Carl Zeiss Meditec AG, Jena, Germany). 
      METHODS: Eighty-two healthy right eyes were enrolled in this prospective 
      observational study. Measurements were repeated for three times using the ZW-30 
      and IOLMaster 700 in a random order. Obtained parameters included axial length 
      (AL), central corneal thickness (CCT), aqueous depth (AQD), anterior chamber 
      depth (ACD), lens thickness (LT), mean keratometry (Km), astigmatism magnitude 
      (AST), vector J(0), vector J(45), and corneal diameter (CD). The within-subject 
      standard deviation (Sw), test-retest (TRT) variability, coefficient of variation 
      (CoV), and intraclass correlation coefficient (ICC) were adopted to assess the 
      intraobserver repeatability and interobserver reproducibility. The double-angle 
      plot was also used to display the distribution of AST. To estimate agreement, 
      Bland-Altman plots were used. RESULTS: For the intraobserver repeatability and 
      interobserver reproducibility, the Sw, TRT and CoV for all parameters were low. 
      Meanwhile, the ICC values were all close to 1.000, except for the J(45) 
      (ICC = 0.887 for the intraobserver repeatability). The double-angle plot showed 
      that the distribution of AST measured by these two devices was similar. For 
      agreement, the Bland-Altman plots showed narrow 95% limits of agreements (LoAs) 
      for AL, CCT, AQD, ACD, LT, Km AST, J(0), J(45), and CD (- 0.02 mm to 
      0.02 mm, - 7.49 mum to 8.08 mum, - 0.07 mm to 0.04 mm, - 0.07 mm to 
      0.04 mm, - 0.07 mm to 0.08 mm, - 0.16 D to 0.30 D, - 0.30 D to 0.29 D, - 0.16 D 
      to 0.16 D, - 0.23 D to 0.13 D, and - 0.39 mm to 0.10 mm, respectively). 
      CONCLUSIONS: The newly dynamic real-time visualization biometer exhibited 
      excellent intraobserver repeatability and interobserver reproducibility. The two 
      devices both based on the SS-OCT principle had similar ocular parameters 
      measurement values and can be interchanged in clinical practice.
CI  - (c) 2024. The Author(s).
FAU - Yu, Jinjin
AU  - Yu J
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
AD  - Ningbo No. 2 Hospital, Ningbo, Zhejiang, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China.
FAU - Lin, Xuanqiao
AU  - Lin X
AD  - Eye Hospital and School of Ophthalmology and Optometry, Wenzhou Medical 
      University, Wenzhou, Zhejiang, China.
FAU - Huang, Xiaomin
AU  - Huang X
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China.
FAU - Xu, Zhenyu
AU  - Xu Z
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China.
FAU - Ning, Rui
AU  - Ning R
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China.
FAU - Li, Kexin
AU  - Li K
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China.
FAU - Savini, Giacomo
AU  - Savini G
AD  - IRCCS Bietti Foundation, Rome, Italy.
FAU - Schiano-Lomoriello, Domenico
AU  - Schiano-Lomoriello D
AD  - IRCCS Bietti Foundation, Rome, Italy.
FAU - Zhou, Xingtao
AU  - Zhou X
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. 
      doctzhouxingtao@163.com.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. 
      doctzhouxingtao@163.com.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China. doctzhouxingtao@163.com.
FAU - Huang, Jinhai
AU  - Huang J
AUID- ORCID: 0000-0001-9952-3175
AD  - Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan 
      University, N No. 19 Baoqing Road, Xuhui District, Shanghai, 200031, China. 
      vip999vip@163.com.
AD  - Shanghai Research Center of Ophthalmology and Optometry, Shanghai, China. 
      vip999vip@163.com.
AD  - NHC Key Laboratory of Myopia (Fudan University), Key Laboratory of Myopia, 
      Chinese Academy of Medical Sciences, Shanghai, China. vip999vip@163.com.
LA  - eng
GR  - 82271048/Project of National Natural Science Foundation of China/
GR  - 22S11900200/Shanghai Science and Technology/
GR  - 23XD1420500/Shanghai Science and Technology/
GR  - 2021318/EYE & ENT Hospital of Fudan University High-level Talents Program/
GR  - SHDC2020CR1043B/Clinical Research Plan of SHDC/
GR  - 2020-015/Project of Shanghai Xuhui District Science and Technology/
GR  - Eastern Scholar/Program for Professor of Special Appointment at Shanghai 
      Institutions of Higher Learning/
GR  - TP2022046/Program for Professor of Special Appointment at Shanghai Institutions 
      of Higher Learning/
GR  - 2022/Fondazione Roma and the Italian Ministry of Health/
PT  - Journal Article
DEP - 20240304
PL  - England
TA  - Eye Vis (Lond)
JT  - Eye and vision (London, England)
JID - 101664982
PMC - PMC10910812
OTO - NOTNLM
OT  - Agreement
OT  - Ocular biometric
OT  - Repeatability
OT  - Reproducibility
OT  - Swept-source optical coherence tomography
COIS- Dr. Savini received lecture fees from Alcon, Johnson & Johnson, SIFI and Zeiss 
      and research grant from Alcon. Other authors have no proprietary or financial 
      interest in any materials discussed in this article.
EDAT- 2024/03/04 00:43
MHDA- 2024/03/04 00:44
PMCR- 2024/03/04
CRDT- 2024/03/03 23:17
PHST- 2023/09/05 00:00 [received]
PHST- 2024/02/10 00:00 [accepted]
PHST- 2024/03/04 00:44 [medline]
PHST- 2024/03/04 00:43 [pubmed]
PHST- 2024/03/03 23:17 [entrez]
PHST- 2024/03/04 00:00 [pmc-release]
AID - 10.1186/s40662-024-00377-2 [pii]
AID - 377 [pii]
AID - 10.1186/s40662-024-00377-2 [doi]
PST - epublish
SO  - Eye Vis (Lond). 2024 Mar 4;11(1):9. doi: 10.1186/s40662-024-00377-2.