PMID- 38434214
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240305
IS  - 2514-2119 (Electronic)
IS  - 2514-2119 (Linking)
VI  - 8
IP  - 3
DP  - 2024 Mar
TI  - Giant aneurysm of the left atrial appendage: a case report.
PG  - ytae099
LID - 10.1093/ehjcr/ytae099 [doi]
LID - ytae099
AB  - BACKGROUND: Left atrial appendage aneurysm (LAAA) is a rare condition mostly due 
      to congenital malformations or secondary causes (i.e. mitral regurgitation). CASE 
      SUMMARY: We present a case of a 47-year-old male with a history of atrial 
      fibrillation treated with propafenone presented to our emergency department for 
      palpitation and epigastric pain. The electrocardiogram showed atrial fibrillation 
      at high ventricular rate and a new-onset left bundle branch block. Urgent 
      coronary angiogram excluded coronary artery disease. Echocardiography and cardiac 
      magnetic resonance revealed a giant LAAA. The electrocardiogram alterations were 
      deemed secondary to aberrancy and treatment with class IC antiarrhythmic. The 
      patient was discussed in the heart team, and considering his will to avoid 
      surgery, he was managed conservatively with closed follow-up, anticoagulant and 
      antiarrhythmic therapy, and internal loop recorder. At 1-year follow-up, he 
      showed asymptomatic and without arrhythmias. DISCUSSION: Few cases are described 
      in the literature; therefore, there is uncertainty in treatment and prognosis. 
      Diagnosis is achieved with multimodality imaging. Treatment can be surgical with 
      aneurysmectomy or conservative with regular follow-up by imaging examinations and 
      pharmacological therapy aimed to prevent complications such as thrombosis and 
      arrhythmias. Since high-quality scientific data are lacking, shared 
      decision-making is essential for the management of patients affected by LAAA. In 
      our clinical case, our patient's will to not undergo surgery was considered, and 
      therefore, a conservative management with strict follow-up and medications was 
      chosen.
CI  - (c) The Author(s) 2024. Published by Oxford University Press on behalf of the 
      European Society of Cardiology.
FAU - Coraducci, Francesca
AU  - Coraducci F
AUID- ORCID: 0009-0008-5893-1293
AD  - Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche 
      University Hospital, Via Conca 71, Ancona 60126, Italy.
FAU - Barbarossa, Alessandro
AU  - Barbarossa A
AD  - Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche 
      University Hospital, Via Conca 71, Ancona 60126, Italy.
FAU - Coretti, Francesca
AU  - Coretti F
AD  - Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche 
      University Hospital, Via Conca 71, Ancona 60126, Italy.
FAU - Belleggia, Sara
AU  - Belleggia S
AD  - Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche 
      University Hospital, Via Conca 71, Ancona 60126, Italy.
FAU - Guerra, Federico
AU  - Guerra F
AUID- ORCID: 0000-0001-5394-1312
AD  - Cardiology and Arrhythmology Clinic, Marche Polytechnic University, Marche 
      University Hospital, Via Conca 71, Ancona 60126, Italy.
LA  - eng
PT  - Case Reports
DEP - 20240220
PL  - England
TA  - Eur Heart J Case Rep
JT  - European heart journal. Case reports
JID - 101730741
PMC - PMC10908382
OTO - NOTNLM
OT  - Atrial fibrillation
OT  - Cardiac magnetic resonance
OT  - Cardiovascular imaging
OT  - Case report
OT  - Echocardiography
OT  - Left atrial appendage aneurysm
COIS- Conflict of interest: None declared.
EDAT- 2024/03/04 06:48
MHDA- 2024/03/04 06:49
PMCR- 2024/02/20
CRDT- 2024/03/04 04:42
PHST- 2023/10/07 00:00 [received]
PHST- 2024/02/11 00:00 [revised]
PHST- 2024/02/15 00:00 [accepted]
PHST- 2024/03/04 06:49 [medline]
PHST- 2024/03/04 06:48 [pubmed]
PHST- 2024/03/04 04:42 [entrez]
PHST- 2024/02/20 00:00 [pmc-release]
AID - ytae099 [pii]
AID - 10.1093/ehjcr/ytae099 [doi]
PST - epublish
SO  - Eur Heart J Case Rep. 2024 Feb 20;8(3):ytae099. doi: 10.1093/ehjcr/ytae099. 
      eCollection 2024 Mar.