PMID- 38434682
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240305
IS  - 2234-943X (Print)
IS  - 2234-943X (Electronic)
IS  - 2234-943X (Linking)
VI  - 14
DP  - 2024
TI  - A Case report: Synovial sarcoma of the mediastinum in an 18-year-old teenager.
PG  - 1288213
LID - 10.3389/fonc.2024.1288213 [doi]
LID - 1288213
AB  - Synovial sarcomas (SSs) are a rare group of malignant tumors originating from 
      pluripotential mesenchymal cells, which commonly occur as the primary tumor in 
      the soft tissues near the articular surface, tendons, and articular synovium. 
      Herein, we report a rare case of mediastinal SS in an 18-year-old teenager who 
      initially presented with cough as the primary symptom. In this case, plain chest 
      CT and contrast-enhanced CT clearly revealed the lesion presenting as a 
      round-like and uneven density mass in the mediastinum with heterogeneous 
      enhancement, which compressed the trachea and invaded the adjacent vessels. Based 
      on the results of immunohistochemistry and fluorescence in situ hybridization 
      (FISH), combined with the differential diagnosis with other types of tumors in 
      the mediastinum on imaging, we were able to diagnose the tumor as an SS located 
      in the mediastinum. Subsequent resection of the lesion coupled with chemotherapy 
      and immunotherapy led to an improvement in the patient's symptoms.
CI  - Copyright (c) 2024 Liu, Cui, Zhou, Zhai, Qin, Fan and Cai.
FAU - Liu, Yan
AU  - Liu Y
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
FAU - Cui, Manman
AU  - Cui M
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
FAU - Zhou, Xiuzhi
AU  - Zhou X
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
FAU - Zhai, Duchang
AU  - Zhai D
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
FAU - Qin, Mingyu
AU  - Qin M
AD  - Suzhou Medical College, Soochow University, Suzhou, China.
FAU - Fan, Guohua
AU  - Fan G
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
FAU - Cai, Wu
AU  - Cai W
AD  - Department of Radiology, The Second Affiliated Hospital of Soochow University, 
      Suzhou, China.
LA  - eng
PT  - Case Reports
DEP - 20240216
PL  - Switzerland
TA  - Front Oncol
JT  - Frontiers in oncology
JID - 101568867
PMC - PMC10904483
OTO - NOTNLM
OT  - chest imaging
OT  - mediastinum
OT  - mesenchymal cell
OT  - oncology
OT  - synovial sarcoma
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2024/03/04 06:51
MHDA- 2024/03/04 06:52
PMCR- 2024/01/01
CRDT- 2024/03/04 04:48
PHST- 2023/09/04 00:00 [received]
PHST- 2024/01/29 00:00 [accepted]
PHST- 2024/03/04 06:52 [medline]
PHST- 2024/03/04 06:51 [pubmed]
PHST- 2024/03/04 04:48 [entrez]
PHST- 2024/01/01 00:00 [pmc-release]
AID - 10.3389/fonc.2024.1288213 [doi]
PST - epublish
SO  - Front Oncol. 2024 Feb 16;14:1288213. doi: 10.3389/fonc.2024.1288213. eCollection 
      2024.