PMID- 38435169
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240305
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 16
IP  - 2
DP  - 2024 Feb
TI  - Adverse Events in Endoscopic Retrograde Cholangiopancreticography for 
      Choledocholithiasis: A Holistic Perspective.
PG  - e53375
LID - 10.7759/cureus.53375 [doi]
LID - e53375
AB  - Background and aims In this study, we aimed to investigate the frequency of 
      adverse events (AEs) in patients undergoing endoscopic retrograde 
      cholangiopancreticography (ERCP) for choledocholithiasis and the independent risk 
      factors that may cause these conditions. We planned to evaluate all AEs including 
      cardiopulmonary complications and the risk factors that may affect them 
      holistically. Methods This study was designed as a retrospective cohort study 
      conducted at a single tertiary center's gastroenterology clinic. The study 
      included patients with naive papillae and undergoing ERCP for choledocholithiasis 
      between May 2019 and June 2022. Risk factors that may lead to AEs were analyzed 
      in terms of both patient-related factors and procedure-related factors. Patients 
      with and without AEs after ERCP were compared. Results This study included 812 
      patients who underwent ERCP for choledocholithiasis. AE occurred in 149 (18.3%) 
      of patients, and the most common complication was pancreatitis (n=112, 13.8%). In 
      regression analysis, of the patient- and procedure-related factors, only 
      difficult cannulation was a significant independent risk factor for AEs (odds 
      ratio=3.85, 95% CI: 1.102-13.498, p=0.035). Conclusion This study showed that, of 
      patient- and procedure-related factors, only difficult cannulation is an 
      independent risk factor for ERCP-related AEs.
CI  - Copyright (c) 2024, Cankurtaran et al.
FAU - Cankurtaran, Rasim Eren
AU  - Cankurtaran RE
AD  - Department of Gastroenterology, Faculty of Medicine, Ankara Yildirim Beyazit 
      University, Ankara, TUR.
FAU - Ersoy, Osman
AU  - Ersoy O
AD  - Department of Gastroenterology, School of Medicine, Ankara Yildirim Beyazit 
      University, Ankara, TUR.
LA  - eng
PT  - Journal Article
DEP - 20240201
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10908872
OTO - NOTNLM
OT  - adverse events (aes)
OT  - choledoccolithiasis
OT  - difficult cannulation
OT  - ercp
OT  - interventional endoscopy
COIS- The authors have declared that no competing interests exist.
EDAT- 2024/03/04 06:42
MHDA- 2024/03/04 06:43
PMCR- 2024/02/01
CRDT- 2024/03/04 04:57
PHST- 2024/01/31 00:00 [accepted]
PHST- 2024/03/04 06:43 [medline]
PHST- 2024/03/04 06:42 [pubmed]
PHST- 2024/03/04 04:57 [entrez]
PHST- 2024/02/01 00:00 [pmc-release]
AID - 10.7759/cureus.53375 [doi]
PST - epublish
SO  - Cureus. 2024 Feb 1;16(2):e53375. doi: 10.7759/cureus.53375. eCollection 2024 Feb.