PMID- 38438752
OWN - NLM
STAT- MEDLINE
DCOM- 20240306
LR  - 20240306
IS  - 1437-9813 (Electronic)
IS  - 0179-0358 (Linking)
VI  - 40
IP  - 1
DP  - 2024 Mar 5
TI  - Kono-S anastomosis in Crohn's disease: initial experience in pediatric patients.
PG  - 67
LID - 10.1007/s00383-024-05648-6 [doi]
AB  - PURPOSE: Children diagnosed with Crohn's disease (CD) often undergo ileocecal 
      resection (ICR) during childhood. Anastomotic recurrence is a frequent finding 
      following this procedure. Data addressing the effect of the anastomosis type on 
      disease recurrence are scarce in the pediatric population. The Kono-S anastomosis 
      has shown promise in reducing endoscopic, clinical, and surgical recurrence rates 
      in adults. We aimed to report our experience with Kono-S anastomosis in children, 
      focusing on its feasibility and postoperative complications. METHODS: We 
      retrospectively analyzed pediatric CD patients who underwent ICR with Kono-S 
      anastomosis between August 2022 and May 2023. Data on demographics, clinical 
      characteristics, surgery, hospitalization, and follow-up including colonoscopy 
      were collected. Complications were classified using the Clavien-Dindo 
      classification. RESULTS: Twelve patients (7 females, 58.3%) were included. Six 
      (50%) of the patients had the B3 luminal form of the disease (according to Paris 
      classification). Median surgery duration was 174 (interquartile range [IQR] 
      161-216) minutes. Anastomosis creation took a median of 62 (IQR, 54.5-71) 
      minutes. Median hospitalization length was 6 (IQR 4-7) days. No short- or 
      mid-term complications were observed. Median follow-up duration was 9.5 (IQR 
      6.8-12) months. CONCLUSION: According to our results, Kono-S anastomosis is safe 
      and feasible in pediatric CD patients, with no observed postoperative 
      complications. These findings support the potential benefit of using Kono-S 
      anastomosis as a treatment approach in children with CD.
CI  - (c) 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Dotlacil, Vojtech
AU  - Dotlacil V
AD  - Department of Paediatric Surgery, Second Faculty of Medicine, Charles University 
      and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, 
      Praha 5, Czech Republic. vojtech.dotlacil@fnmotol.cz.
FAU - Lerchova, Tereza
AU  - Lerchova T
AD  - Department of Paediatrics, Second Faculty of Medicine, Charles University and 
      Motol University Hospital, Prague, Czech Republic.
FAU - Lengalova, Marketa
AU  - Lengalova M
AD  - Department of Surgery, NH Hospital a.s., Horovice, Czech Republic.
FAU - Kucerova, Barbora
AU  - Kucerova B
AD  - Department of Paediatric Surgery, Second Faculty of Medicine, Charles University 
      and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, 
      Praha 5, Czech Republic.
FAU - Schwarz, Jan
AU  - Schwarz J
AD  - Department of Paediatrics, Faculty of Medicine in Pilsen, Faculty Hospital, 
      Charles University in Prague, Pilsen, Czech Republic.
FAU - Hradsky, Ondrej
AU  - Hradsky O
AD  - Department of Paediatrics, Second Faculty of Medicine, Charles University and 
      Motol University Hospital, Prague, Czech Republic.
FAU - Rygl, Michal
AU  - Rygl M
AD  - Department of Paediatric Surgery, Second Faculty of Medicine, Charles University 
      and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, 
      Praha 5, Czech Republic.
FAU - Skaba, Richard
AU  - Skaba R
AD  - Department of Paediatric Surgery, Second Faculty of Medicine, Charles University 
      and Motol University Hospital, Prague, Charles University, V Uvalu 84, 150 06, 
      Praha 5, Czech Republic.
LA  - eng
PT  - Journal Article
DEP - 20240305
PL  - Germany
TA  - Pediatr Surg Int
JT  - Pediatric surgery international
JID - 8609169
RN  - Pediatric Crohn's disease
SB  - IM
MH  - Adult
MH  - Female
MH  - Humans
MH  - Child
MH  - *Crohn Disease/surgery
MH  - Retrospective Studies
MH  - Anastomosis, Surgical
MH  - Postoperative Complications/epidemiology
OTO - NOTNLM
OT  - Crohn's disease
OT  - Endoscopy
OT  - Kono-S
OT  - Pediatric surgery
OT  - Postoperative complication
EDAT- 2024/03/05 00:45
MHDA- 2024/03/06 06:43
CRDT- 2024/03/04 23:37
PHST- 2024/01/30 00:00 [accepted]
PHST- 2024/03/06 06:43 [medline]
PHST- 2024/03/05 00:45 [pubmed]
PHST- 2024/03/04 23:37 [entrez]
AID - 10.1007/s00383-024-05648-6 [pii]
AID - 10.1007/s00383-024-05648-6 [doi]
PST - epublish
SO  - Pediatr Surg Int. 2024 Mar 5;40(1):67. doi: 10.1007/s00383-024-05648-6.