PMID- 38447036 OWN - NLM STAT- MEDLINE DCOM- 20240308 LR - 20240308 IS - 1877-8879 (Electronic) IS - 1877-8860 (Linking) VI - 24 IP - 1 DP - 2024 Jan 1 TI - Confirmatory study of the usefulness of quantum molecular resonance and microdissectomy for the treatment of lumbar radiculopathy in a prospective cohort at 6 months follow-up. LID - 10.1515/sjpain-2023-0077 [doi] AB - OBJECTIVES: Low back pain is a common musculoskeletal complaint and while prognosis is usually favorable, some patients experience persistent pain despite conservative treatment and invasive treatment to target the root cause of the pain may be necessary. The aim of this study is to evaluate patient outcomes after treatment of lumbar radiculopathy (LR) with quantum molecular resonance radiofrequency coblation disc decompression and percutaneous microdiscectomy with grasper forceps (QMRG). METHODS: This prospective cohort study was carried out in two Spanish hospitals on 58 patients with LR secondary to a contained hydrated lumbar disc hernia or lumbar disc protrusion of more than 6 months of evolution, which persisted despite conservative treatment with analgesia, rehabilitation, and physiotherapy, and/or epidural block, in the previous 2 years. Patients were treated with QMRG and the outcomes were measured mainly using the Douleur Neuropathique en 4 Questions, Numeric Rating Scale, Oswestry Disability Index, SF12: Short Form 12 Health Survey, Patient Global Impression of Improvement, Clinical Global Impression of Improvement, and Medical Outcomes Study Sleep Scale. RESULTS: Patients who received QMRG showed significant improvement in their baseline scores at 6 months post-treatment. The minimal clinically important difference (MCID) threshold was met by 26-98% of patients, depending on the outcome measure, for non-sleep-related outcomes, and between 17 and 62% for sleep-related outcome measures. Of the 14 outcome measures studied, at least 50% of the patients met the MCID threshold in 8 of them. CONCLUSION: Treatment of LR with QMRG appears to be effective at 6 months post-intervention. CI - (c) 2024 the author(s), published by De Gruyter. FAU - Canos-Verdecho, Angeles AU - Canos-Verdecho A AD - Multidisciplinary Pain Management Unit, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. AD - Anaesthesiology Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Robledo, Ruth AU - Robledo R AD - Multidisciplinary Pain Management Unit, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. AD - Anaesthesiology Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Izquierdo, Rosa AU - Izquierdo R AD - Multidisciplinary Pain Management Unit, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. AD - Anaesthesiology Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Bermejo, Ara AU - Bermejo A AD - Multidisciplinary Pain Management Unit, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Gallach, Elisa AU - Gallach E AD - Multidisciplinary Pain Management Unit, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. AD - Psychiatry Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Abejon, David AU - Abejon D AD - Multidisciplinary Pain Management Unit, Hospital Universitario Quironsalud, Calle Diego de Velazquez, 1, 28223 Pozuelo de Alarcon, Madrid, Spain. FAU - Argente, Pilar AU - Argente P AD - Anaesthesiology Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. AD - Surgical Specialities Department, Hospital Universitari i Politecnic La Fe, Av. de Fernando Abril Martorell, 106, 46026 Valencia, Spain. FAU - Peraita-Costa, Isabel AU - Peraita-Costa I AD - Unit of Preventive Medicine and Public Health, Department of Preventive Medicine and Public Health, Food Sciencs, Toxicology and Forensic Medicine, Universitat de Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia, Spain. AD - CIBER Epidemiology and Public Health (CIBERESP), The Institute of Health Carlos III (ISCIII), Av. Monforte de Lemos, 3-5, Pabellon 11, Planta 0, 28029 Madrid, Spain. FAU - Morales-Suarez-Varela, Maria AU - Morales-Suarez-Varela M AD - Unit of Preventive Medicine and Public Health, Department of Preventive Medicine and Public Health, Food Sciencs, Toxicology and Forensic Medicine, Universitat de Valencia, Av. Vicent Andres Estelles s/n, 46100 Burjassot, Valencia, Spain. AD - CIBER Epidemiology and Public Health (CIBERESP), The Institute of Health Carlos III (ISCIII), Av. Monforte de Lemos, 3-5, Pabellon 11, Planta 0, 28029 Madrid, Spain. LA - eng PT - Journal Article DEP - 20240306 PL - Germany TA - Scand J Pain JT - Scandinavian journal of pain JID - 101520867 SB - IM MH - Humans MH - Prospective Studies MH - *Radiculopathy/surgery MH - Follow-Up Studies MH - Pain Management MH - *Low Back Pain/surgery OTO - NOTNLM OT - lumbar radiculopathy OT - nucleoplasty OT - prospective cohort OT - quantum molecular resonance OT - radiofrequency coblation EDAT- 2024/03/06 18:42 MHDA- 2024/03/08 06:42 CRDT- 2024/03/06 15:12 PHST- 2023/06/12 00:00 [received] PHST- 2023/12/07 00:00 [accepted] PHST- 2024/03/08 06:42 [medline] PHST- 2024/03/06 18:42 [pubmed] PHST- 2024/03/06 15:12 [entrez] AID - sjpain-2023-0077 [pii] AID - 10.1515/sjpain-2023-0077 [doi] PST - epublish SO - Scand J Pain. 2024 Mar 6;24(1). doi: 10.1515/sjpain-2023-0077. eCollection 2024 Jan 1.