PMID- 38451885 OWN - NLM STAT- MEDLINE DCOM- 20240311 LR - 20240311 IS - 1932-6203 (Electronic) IS - 1932-6203 (Linking) VI - 19 IP - 3 DP - 2024 TI - Diminished psychedelic returns on distress: Marital status and household size. PG - e0293675 LID - 10.1371/journal.pone.0293675 [doi] LID - e0293675 AB - Although the use of psychedelics to impact health has seen growth, little research has tested the effects of culture conditions on the relationship. More specifically, how does marital status and family size affect the relationship between psychedelics and health? This study tests the relationship between Lifetime Classic Psychedelic Use (LCPU), marital status, and household size (number of people living in a household) on levels of psychological distress in the past 30 days. This project uses pooled data from the National Survey of Drug Use and Health (NSDUH) (2010 to 2018) (N = 674,521). The Final sample size is determined by the dependent variable, psychological distress in the past month (n = 158,633). The analysis includes a series of nested logistic regression models conducted in Stata 17. Results indicate that LCPU is independently associated with better health, but the association between LCPU and health varies across levels of household size. Larger households are associated with higher levels of distress, which are then exacerbated among psychedelics users. Furthermore, three-way interactions reveal that the negative association between household size and distress gets larger among psychedelic users who are married, divorced, and widowed. Overall, results suggest that household size negatively impacts the association between LCPU and health, with those who are married, divorced, and widowed experiencing the worst outcomes. CI - Copyright: (c) 2024 Sean M. Vina. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. FAU - Vina, Sean M AU - Vina SM AUID- ORCID: 0000-0002-7125-0192 AD - Department of Sociology, The University of the Incarnate Word, San Antonio, Texas, United States of America. LA - eng PT - Journal Article DEP - 20240307 PL - United States TA - PLoS One JT - PloS one JID - 101285081 RN - 0 (Hallucinogens) SB - IM MH - Humans MH - *Hallucinogens MH - Marital Status MH - Marriage/psychology MH - Family Characteristics MH - Divorce PMC - PMC10919602 COIS- The authors have declared that no competing interests exist. EDAT- 2024/03/07 18:42 MHDA- 2024/03/11 06:43 PMCR- 2024/03/07 CRDT- 2024/03/07 13:33 PHST- 2023/05/04 00:00 [received] PHST- 2023/10/18 00:00 [accepted] PHST- 2024/03/11 06:43 [medline] PHST- 2024/03/07 18:42 [pubmed] PHST- 2024/03/07 13:33 [entrez] PHST- 2024/03/07 00:00 [pmc-release] AID - PONE-D-23-13323 [pii] AID - 10.1371/journal.pone.0293675 [doi] PST - epublish SO - PLoS One. 2024 Mar 7;19(3):e0293675. doi: 10.1371/journal.pone.0293675. eCollection 2024.