PMID- 38454981
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240309
IS  - 2807-2618 (Electronic)
IS  - 2807-2618 (Linking)
VI  - 3
IP  - 2
DP  - 2023 Aug
TI  - Celiac disease: Pathogenesis, disease management and new insights into the 
      herbal-based treatments.
PG  - e147
LID - 10.52225/narra.v3i2.147 [doi]
LID - e147
AB  - Celiac disease (CD) is a gluten intolerance autoimmune disorder which its 
      symptoms involve the gastrointestinal tract and sometimes the other organs. It is 
      one of the most prevalent health problems rising in many populations as 
      statistics show that in every 100 people about one person is suffering from CD. 
      It has been observed that the persons who genetically contain the human leukocyte 
      antigen (HLA) DQ2 and HLA DQ8 genes involved in the immune system haplotypes are 
      more prone to develop an allergy to gluten. The only treatment currently 
      available for CD is a strict gluten-free diet. However, recent research has shown 
      promising new insights into the herbal-based treatments of CD. New insight on CD 
      is now offering various prospects to manage its treatment, diagnosis, and serving 
      in the development of advanced therapies. Several herbs and botanical extracts 
      have demonstrated anti-inflammatory, immunomodulatory, and gut-healing properties 
      that make them potential candidates for the management of CD. Here, we provide an 
      updated review on pathogeneses and managements of CD. In particular, we summarize 
      the current understandings of herbal-based treatments for CD and highlights their 
      potential benefits.
CI  - (c) 2023 The Author(s).
FAU - Mittal, Pooja
AU  - Mittal P
AD  - Chitkara College of Pharmacy, Chitkara University, Rajpura, India.
FAU - Arora, Disha
AU  - Arora D
AD  - Chandigarh College of Pharmacy, CGC Landran, Mohali, India.
FAU - Parashar, Smriti
AU  - Parashar S
AD  - Vedic Institute of Pharmaceutical Education and Research, Sagar, India.
FAU - Goyal, Rajat
AU  - Goyal R
AD  - MM College of Pharmacy, Maharishi Markandeshwar (Deemed to be University), 
      Mullana, India.
FAU - Khan, Amir
AU  - Khan A
AD  - Chitkara College of Pharmacy, Chitkara University, Rajpura, India.
FAU - Chopra, Hitesh
AU  - Chopra H
AD  - Chitkara College of Pharmacy, Chitkara University, Rajpura, India.
FAU - Mishra, Dinesh K
AU  - Mishra DK
AD  - Indore Institute of Pharmacy, IIST Campus, Indore, India.
FAU - Gautam, Rupesh K
AU  - Gautam RK
AD  - Indore Institute of Pharmacy, IIST Campus, Indore, India.
FAU - Dhama, Kuldeep
AU  - Dhama K
AD  - Division of Pathology, ICAR-Indian Veterinary Research Institute, Izatnagar, 
      India.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230712
PL  - Indonesia
TA  - Narra J
JT  - Narra J
JID - 9918625888906676
PMC - PMC10919711
OTO - NOTNLM
OT  - Celiac disease
OT  - autoimmune disorder
OT  - genetic
OT  - gluten
OT  - human leukocyte antigen
COIS- All the authors declare that there are no conflicts of interest.
EDAT- 2024/03/08 06:43
MHDA- 2024/03/08 06:44
PMCR- 2023/07/12
CRDT- 2024/03/08 03:55
PHST- 2023/04/11 00:00 [received]
PHST- 2023/07/04 00:00 [accepted]
PHST- 2024/03/08 06:44 [medline]
PHST- 2024/03/08 06:43 [pubmed]
PHST- 2024/03/08 03:55 [entrez]
PHST- 2023/07/12 00:00 [pmc-release]
AID - NarraJ-3-e147 [pii]
AID - 10.52225/narra.v3i2.147 [doi]
PST - ppublish
SO  - Narra J. 2023 Aug;3(2):e147. doi: 10.52225/narra.v3i2.147. Epub 2023 Jul 12.