PMID- 38456116 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240309 IS - 1394-195X (Print) IS - 2180-4303 (Electronic) IS - 1394-195X (Linking) VI - 31 IP - 1 DP - 2024 Feb TI - Ligation of the Intersphincteric Fistula Tract as an Emergency Treatment for Cryptoglandular Anal Fistula. PG - 62-70 LID - 10.21315/mjms2024.31.1.5 [doi] AB - INTRODUCTION: Ligation of the intersphincteric fistula tract (LIFT) is a sphincter-preserving procedure for treating anal fistula of cryptoglandular origin. Our prospective study aimed to determine the postoperative outcomes of patients undergoing LIFT in emergency and elective settings. METHODS: This was a single-centre prospective observational study of the LIFT procedure for the treatment of anal fistulas. The differences in the 6-month postoperative outcomes between the emergency and elective procedures were analysed, including the healing rate, healing time, recurrence rate, recurrence time, postoperative complications and length of hospital stay. RESULTS: Twenty-two patients were recruited for this study: 11 patients underwent LIFT as an emergency procedure (EM-LIFT), while the others underwent LIFT as an elective procedure (EL-LIFT). The healing rate for the EM-LIFT group was 90.9% (n = 10), with a median healing time of 2 months (range 0.5-4). For the EL-LIFT group, the healing rate was 100% (n = 11), with the same median healing time of 2 months (range 0.5-4). Two of the patients in the EM-LIFT group developed recurrence, with a median recurrence time of 5 months (range 4-6) and three developed recurrence in the EL-LIFT group, with the same median recurrence time of 5 months (range 4-6). There were minor postoperative complications of pain and subcutaneous infection, with no faecal incontinence. There was no statistically significant difference in postoperative outcomes between the groups. CONCLUSION: EM-LIFT is a feasible and safe primary procedure for active cryptoglandular-type anal fistulas. CI - (c) Penerbit Universiti Sains Malaysia, 2024. FAU - Dualim, Diana Melissa AU - Dualim DM AD - Colorectal Unit, Department of Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. FAU - Wong, Michael Pak-Kai AU - Wong MP AD - School of Medical Sciences and Hospital Universiti Sains Malaysia, Universiti Sains Malaysia, Kelantan, Malaysia. FAU - Rusli, Siti Mayuha AU - Rusli SM AD - Colorectal Unit, Department of Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. FAU - Elnaim Ali, Abdel Latif Khalifa AU - Elnaim Ali ALK AD - Department of Surgery, Kassala Police Hospital, Kassala, Sudan. FAU - Sagap, Ismail AU - Sagap I AD - Colorectal Unit, Department of Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia. LA - eng PT - Journal Article DEP - 20240228 PL - Malaysia TA - Malays J Med Sci JT - The Malaysian journal of medical sciences : MJMS JID - 101126308 PMC - PMC10917591 OTO - NOTNLM OT - abscess OT - anal fistula OT - elective surgical procedures OT - emergency treatment OT - ligation COIS- Conflict of Interest: None. EDAT- 2024/03/08 06:43 MHDA- 2024/03/08 06:44 PMCR- 2024/02/01 CRDT- 2024/03/08 04:09 PHST- 2022/08/03 00:00 [received] PHST- 2023/04/06 00:00 [accepted] PHST- 2024/03/08 06:44 [medline] PHST- 2024/03/08 06:43 [pubmed] PHST- 2024/03/08 04:09 [entrez] PHST- 2024/02/01 00:00 [pmc-release] AID - 05mjms3101_oa [pii] AID - 10.21315/mjms2024.31.1.5 [doi] PST - ppublish SO - Malays J Med Sci. 2024 Feb;31(1):62-70. doi: 10.21315/mjms2024.31.1.5. Epub 2024 Feb 28.