PMID- 38469591
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240313
IS  - 1664-2295 (Print)
IS  - 1664-2295 (Electronic)
IS  - 1664-2295 (Linking)
VI  - 15
DP  - 2024
TI  - Curative effect analysis of robot-assisted drainage surgery in treatment of 
      spontaneous hypertensive brainstem hemorrhage.
PG  - 1352949
LID - 10.3389/fneur.2024.1352949 [doi]
LID - 1352949
AB  - OBJECTIVE: Spontaneous hypertensive brainstem hemorrhage (HBSH) is characterized 
      by sudden onset, rapid progression and poor prognosis. There has been a growing 
      tendency of surgical treatment for HBSH. This study aimed to investigate outcomes 
      and potential factors associated with the prognosis of robot-assisted drainage 
      surgery for HBSH treatment. METHODS: Patients with HBSH from July 2016 to March 
      2023 at a single neurosurgery center were included and divided into conservative 
      group and surgical groups. Baseline and clinical data, radiographic 
      characteristics, complications, and outcome evaluations were recorded and 
      analyzed. RESULTS: A total of 125 patients, with 74 in the conservative group and 
      51 in the surgical group, were enrolled in the study. Mortality at 6 months was 
      59/74 (79.7%) in the conservative group and 9/51 (17.6%) in the surgical group. 
      Twenty-four patients (47.1%) achieved favorable outcomes in the surgical group, 
      whereas this rate in the conservative group was only 5.4% (4/74). There was a 
      significant difference in NIHSS, GCS, and mRS at 6 months between surviving 
      patients in the conservative and surgical groups. In prognostic analysis in the 
      surgical subgroup, initial GCS score [5 (IQR 4-7) vs. 3 (IQR 3-4), p < 0.001], 
      NIHSS [36 (IQR 32-38) vs. 40 (IQR 38-40), p < 0.001], smoking history [45.8% 
      (11/24) vs. 74.1% (20/27), p = 0.039], hematoma volume [6.9 (IQR 6.2-7.6) vs. 9.6 
      (IQR 7.3-11.4), p = 0.001], and hemorrhage location (p = 0.001) were potential 
      risk factors for poor 6-month prognosis after robot-assisted surgery for HBSH. 
      CONCLUSION: Based on the results of this study, robot-assisted minimally invasive 
      drainage of brain stem hematoma may significantly reduce mortality and improve 
      prognosis. Surgery should be conducted for selected patients.
CI  - Copyright (c) 2024 Tang, Huang, Chen, Guo, Zheng, Wei, Jiang and Yang.
FAU - Tang, Zhiji
AU  - Tang Z
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Huang, Weilong
AU  - Huang W
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Chen, Qiqi
AU  - Chen Q
AD  - Department of Magnetoencephalography, Nanjing Brain Hospital Affiliated to 
      Nanjing Medical University, Nanjing, China.
FAU - Guo, Changgui
AU  - Guo C
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Zheng, Kuan
AU  - Zheng K
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Wei, Wenjin
AU  - Wei W
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Jiang, Qiuhua
AU  - Jiang Q
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
FAU - Yang, Ruijin
AU  - Yang R
AD  - Department of Neurosurgery, Ganzhou People's Hospital, Ganzhou, Jiangxi, China.
LA  - eng
PT  - Journal Article
DEP - 20240226
PL  - Switzerland
TA  - Front Neurol
JT  - Frontiers in neurology
JID - 101546899
PMC - PMC10925720
OTO - NOTNLM
OT  - prognosis
OT  - robot-assisted drainage
OT  - spontaneous hypertensive brainstem hemorrhage
OT  - stereotactic system
OT  - surgical treatment
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2024/03/12 06:42
MHDA- 2024/03/12 06:43
PMCR- 2024/02/26
CRDT- 2024/03/12 03:59
PHST- 2023/12/15 00:00 [received]
PHST- 2024/02/13 00:00 [accepted]
PHST- 2024/03/12 06:43 [medline]
PHST- 2024/03/12 06:42 [pubmed]
PHST- 2024/03/12 03:59 [entrez]
PHST- 2024/02/26 00:00 [pmc-release]
AID - 10.3389/fneur.2024.1352949 [doi]
PST - epublish
SO  - Front Neurol. 2024 Feb 26;15:1352949. doi: 10.3389/fneur.2024.1352949. 
      eCollection 2024.