PMID- 38473066
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240315
IS  - 2076-2615 (Print)
IS  - 2076-2615 (Electronic)
IS  - 2076-2615 (Linking)
VI  - 14
IP  - 5
DP  - 2024 Feb 21
TI  - Updating the Classification of Chronic Inflammatory Enteropathies in Dogs.
LID - 10.3390/ani14050681 [doi]
LID - 681
AB  - Chronic inflammatory enteropathies (CIEs) in dogs are currently classified based 
      on response to sequential treatment trials into food-responsive (FREs); 
      antibiotic-responsive (AREs); immunosuppressant-responsive (IREs); and 
      non-responsive enteropathies (NREs). Recent studies have reported that a 
      proportion of NRE dogs ultimately respond to further dietary trials and are 
      subsequently misclassified. The FRE subset among CIEs is therefore probably 
      underestimated. Moreover, alterations in the gut microbiota composition and 
      function (dysbiosis) have been shown to be involved in CIE pathogenesis in recent 
      research on dogs. Metronidazole and other antibiotics that have been used for 
      decades for dogs with AREs have been demonstrated to result in increased 
      antimicrobial resistance and deleterious effects on the gut microbiota. As a 
      consequence, the clinical approach to CIEs has evolved in recent years toward the 
      gradual abandonment of the use of antibiotics and their replacement by other 
      treatments with the aim of restoring a diverse and functional gut microbiota. We 
      propose here to refine the classification of canine CIEs by replacing the AREs 
      category with a microbiota-related modulation-responsive enteropathies (MrMREs) 
      category.
FAU - Dupouy-Manescau, Noemie
AU  - Dupouy-Manescau N
AD  - Oniris VetAgroBio Nantes, Department of Clinical Sciences, Nantes-Atlantic 
      College of Veterinary Medicine and Food Sciences, 44300 Nantes, France.
FAU - Meric, Tristan
AU  - Meric T
AUID- ORCID: 0000-0001-8869-0226
AD  - Oniris VetAgroBio Nantes, Department of Clinical Sciences, Nantes-Atlantic 
      College of Veterinary Medicine and Food Sciences, 44300 Nantes, France.
FAU - Senecat, Odile
AU  - Senecat O
AD  - Oniris VetAgroBio Nantes, Department of Clinical Sciences, Nantes-Atlantic 
      College of Veterinary Medicine and Food Sciences, 44300 Nantes, France.
FAU - Drut, Amandine
AU  - Drut A
AUID- ORCID: 0000-0002-8700-6004
AD  - Oniris VetAgroBio Nantes, Department of Clinical Sciences, Nantes-Atlantic 
      College of Veterinary Medicine and Food Sciences, 44300 Nantes, France.
AD  - Microbiota Interaction with Human and Animal Team (MIHA), Micalis Institute, 
      AgrosParisTech, Universite Paris-Saclay, Institut National de Recherche pour 
      l'Agriculture, l'Alimentation et l'Environnement, 78350 Jouy-en-Josas, France.
FAU - Valentin, Suzy
AU  - Valentin S
AUID- ORCID: 0000-0002-8585-3517
AD  - Hopia, Bozon Veterinary Clinic, 78280 Guyancourt, France.
FAU - Leal, Rodolfo Oliveira
AU  - Leal RO
AUID- ORCID: 0000-0002-2463-4062
AD  - Associate Laboratory for Animal and Veterinary Sciences, AL4AnimalS, CIISA-Centre 
      for Interdisciplinary Research in Animal Health, Faculty of Veterinary Medicine, 
      University of Lisbon, 1649-004 Lisbon, Portugal.
FAU - Hernandez, Juan
AU  - Hernandez J
AUID- ORCID: 0000-0002-2093-1692
AD  - Oniris VetAgroBio Nantes, Department of Clinical Sciences, Nantes-Atlantic 
      College of Veterinary Medicine and Food Sciences, 44300 Nantes, France.
AD  - Microbiota Interaction with Human and Animal Team (MIHA), Micalis Institute, 
      AgrosParisTech, Universite Paris-Saclay, Institut National de Recherche pour 
      l'Agriculture, l'Alimentation et l'Environnement, 78350 Jouy-en-Josas, France.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240221
PL  - Switzerland
TA  - Animals (Basel)
JT  - Animals : an open access journal from MDPI
JID - 101635614
PMC - PMC10931249
OTO - NOTNLM
OT  - chronic inflammatory enteropathies
OT  - classification
OT  - dogs
OT  - dysbiosis
OT  - microbiota modulation
COIS- T.M. and J.H. have research funding by Royal Canin((R)). ROL has also benefited 
      from research funding by Royal Canin((R)), Hill's((R)) and Purina((R)). All these 
      manufacturers market hydrolyzed diets for dogs.
EDAT- 2024/03/13 06:46
MHDA- 2024/03/13 06:47
PMCR- 2024/02/21
CRDT- 2024/03/13 01:18
PHST- 2023/12/29 00:00 [received]
PHST- 2024/02/08 00:00 [revised]
PHST- 2024/02/20 00:00 [accepted]
PHST- 2024/03/13 06:47 [medline]
PHST- 2024/03/13 06:46 [pubmed]
PHST- 2024/03/13 01:18 [entrez]
PHST- 2024/02/21 00:00 [pmc-release]
AID - ani14050681 [pii]
AID - animals-14-00681 [pii]
AID - 10.3390/ani14050681 [doi]
PST - epublish
SO  - Animals (Basel). 2024 Feb 21;14(5):681. doi: 10.3390/ani14050681.