PMID- 38476375 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240314 IS - 2297-055X (Print) IS - 2297-055X (Electronic) IS - 2297-055X (Linking) VI - 11 DP - 2024 TI - Simultaneous management of aortic and mitral regurgitation through one-stage transcatheter aortic valve replacement and transcatheter edge-to-edge repair: case report. PG - 1346022 LID - 10.3389/fcvm.2024.1346022 [doi] LID - 1346022 AB - This case report presents a 72-year-old male patient who presented with exertional dyspnea for over 10 years, which had progressively worsened over the past 4 months. Transthoracic echocardiography revealed severe aortic and mitral regurgitation, with a left ventricular ejection fraction of 37% and a left ventricular end-diastolic diameter of 64 mm. Despite receiving long-term optimal medical management, there was no improvement in symptoms or severity of valvular regurgitation. Given the relatively high surgical risk associated with double valve replacement in this elderly patient and his preference for minimally invasive procedures, a one-stage transapical aortic valve replacement and transcatheter mitral valve repair using the edge-to-edge technique were planned. The patient was discharged 8 days post-procedure without any complications. At 1-month follow-up, the patient's New York Heart Association (NYHA) functional class had improved to grade II. CI - (c) 2024 Lin, Zhu, Lv and Wang. FAU - Lin, Hao AU - Lin H AD - Department of Cardiovascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. FAU - Zhu, Mei AU - Zhu M AD - Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. FAU - Lv, Meng AU - Lv M AD - Department of Ultrasound, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. FAU - Wang, Zhengjun AU - Wang Z AD - Department of Cardiovascular Surgery, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China. LA - eng PT - Case Reports DEP - 20240227 PL - Switzerland TA - Front Cardiovasc Med JT - Frontiers in cardiovascular medicine JID - 101653388 PMC - PMC10927942 OTO - NOTNLM OT - aortic insufficiency OT - case report OT - mitral regurgitation OT - transcatheter aortic valve replacement OT - transcatheter edge-to-edge mitral valve repair COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2024/03/13 06:46 MHDA- 2024/03/13 06:47 PMCR- 2024/01/01 CRDT- 2024/03/13 03:51 PHST- 2023/11/28 00:00 [received] PHST- 2024/02/05 00:00 [accepted] PHST- 2024/03/13 06:47 [medline] PHST- 2024/03/13 06:46 [pubmed] PHST- 2024/03/13 03:51 [entrez] PHST- 2024/01/01 00:00 [pmc-release] AID - 10.3389/fcvm.2024.1346022 [doi] PST - epublish SO - Front Cardiovasc Med. 2024 Feb 27;11:1346022. doi: 10.3389/fcvm.2024.1346022. eCollection 2024.