PMID- 38477205 OWN - NLM STAT- Publisher LR - 20240313 IS - 1573-4056 (Electronic) DP - 2024 Feb 21 TI - Relationships between Size-specific Dose Estimate and Signal to Noise Ratio under Chest CT Examinations with Tube Current Modulation. LID - 10.2174/0115734056267251231121064259 [doi] AB - PURPOSE: Exploring the relationship between the signal-to-noise ratio (SNR) of organs and size-specific dose estimate (SSDE) in tube current modulation (TCM) chest CT examination. METHODS: Forty patients who received TCM chest CT scanning were retrospectively collected and divided into four groups according to the tube voltage and sexes. We chose to set up the region of interest (ROI) at the tracheal bifurcation and its upper and lower parts in slice images of the heart, aorta, lungs, paracranial muscles, and female breast, and the SNR of each organ was calculated. We also calculated the corresponding axial volume CT dose index (CTDIvolz) and axial size-specific dose estimate (SSDEz). RESULTS: The correlation analysis showed that the correlation between the SNR of the slice images of most organs and SSDEz was more significant than 0.8, and that between the SNR and CTDIvol was more significant than 0.7. The simple linear regression analysis results showed that when the sex is the same, the SNR of the same organ at 100kVp was higher than 120kVp, except for the lung. In multiple regression analysis, the result indicated that the determination coefficients of the SNR and SSDEz of the four groups were 0.934, 0.971, 0.905, and 0.709, respectively. CONCLUSION: In chest CT examinations with TCM, the correlation between the SNR of each organ in slice images and SSDEz was better than that of CTDIvolz. And when the SSDEz was the same, the SNR at 100 kVp was better than that at 120 kVp. CI - Copyright(c) Bentham Science Publishers; For any queries, please email at epub@benthamscience.net. FAU - Qin, Tian AU - Qin T AUID- ORCID: 0000-0003-0112-1982 AD - School of Medical Imaging, Bengbu Medical College, Bengbu, China. FAU - Wang, Jing AU - Wang J AUID- ORCID: 0009-0001-7554-1210 AD - School of Medical Imaging, Bengbu Medical College, Bengbu, China. FAU - Wang, Mengting AU - Wang M AUID- ORCID: 0009-0002-4027-0243 AD - School of Medical Imaging, Bengbu Medical College, Bengbu, China. FAU - Gu, Ye AU - Gu Y AUID- ORCID: 0009-0000-3861-3302 AD - School of Medical Imaging, Bengbu Medical College, Bengbu, China. FAU - Xie, Zongyu AU - Xie Z AUID- ORCID: 0000-0002-7059-5260 AD - The First Affiliated Hospital of Bengbu Medical College, No. 287 Changhuai Road, Bengbu, Anhui 233004, China. FAU - Liang, Baohui AU - Liang B AUID- ORCID: 0000-0003-4901-5994 AD - School of Medical Imaging, Bengbu Medical College, Bengbu, China. LA - eng PT - Journal Article DEP - 20240221 PL - United Arab Emirates TA - Curr Med Imaging JT - Current medical imaging JID - 101762461 SB - IM OTO - NOTNLM OT - Automatic tube current modulation OT - Chest computed tomography (CT) OT - ROI. OT - Signal-tonoise ratio OT - Size-specific dose estimate OT - Volume CT dose index EDAT- 2024/03/13 06:46 MHDA- 2024/03/13 06:46 CRDT- 2024/03/13 05:33 PHST- 2023/08/02 00:00 [received] PHST- 2023/10/02 00:00 [revised] PHST- 2023/10/16 00:00 [accepted] PHST- 2024/03/13 06:46 [medline] PHST- 2024/03/13 06:46 [pubmed] PHST- 2024/03/13 05:33 [entrez] AID - CMIR-EPUB-138640 [pii] AID - 10.2174/0115734056267251231121064259 [doi] PST - aheadofprint SO - Curr Med Imaging. 2024 Feb 21. doi: 10.2174/0115734056267251231121064259.