PMID- 38479097
OWN - NLM
STAT- MEDLINE
DCOM- 20240430
LR  - 20240430
IS  - 1525-3171 (Electronic)
IS  - 0032-5791 (Print)
IS  - 0032-5791 (Linking)
VI  - 103
IP  - 5
DP  - 2024 May
TI  - Effects of dietary Artemisia annua supplementation on growth performance, 
      antioxidant capacity, immune function, and gut microbiota of geese.
PG  - 103594
LID - S0032-5791(24)00173-1 [pii]
LID - 10.1016/j.psj.2024.103594 [doi]
LID - 103594
AB  - This experiment aimed to study the effect of 1% Artemisia annua added to the diet 
      on growth performance, antioxidant capacity, immunity and intestinal morphology, 
      and gut microbiota of geese. Seventy-two 35-day-old male geese (Zi goose) with 
      similar body weight were selected and randomly divided into 2 groups. Each 
      treatment group of 36 geese was divided into 6 subgroups, each having 6 male 
      geese. The experiment lasted for 21 d. Control group (CON) was fed a basal diet 
      and the experimental group (AAL) was fed a basal diet + 1% Artemisia annua. BW, 
      ADG, and ADFI of the AAL group increased (p < 0.05) and the FCR decreased (p < 
      0.05) compared with the CON group. The addition of Artemisia annua to the diet 
      increased catalase (CAT), glutathione peroxidase (GSH-px), and superoxide 
      dismutase (SOD) enzyme activities, increased total antioxidant capacity (T-AOC), 
      and decreased malondialdehyde (MDA) content in serum and jejunum of geese (p < 
      0.05). Meanwhile, serum IgA, IgG, IgM, and lysozyme (LZM), increased at different 
      time points in the AAL group compared to the CON group (p < 0.05), and decrease 
      in the content of interferon-gamma (IFN-gamma) , IL-6 (p < 0.05), but no effect on 
      complement C3 and C4. Morphological observation of the small intestine showed 
      that the jejunal crypt depth was decreased in the AAL group (p < 0.05) while 
      elevating the jejunal villus height/crypt depth (p < 0.05). 16S rRNA sequencing 
      results showed the Artemisia annua increased the diversity of cecum microbiota, 
      increasing the relative abundance of Bacteroides, Fecalibacterium, and 
      Paraprevotella. In conclusion, the addition of 1% Artemisia annua to the diet 
      could improve the growth performance, antioxidant and immune ability of geese, as 
      well as improve the development of the jejunum intestinal tract of geese, and 
      change the structure of the cecum microbiota, which had a positive effect on the 
      growth and development of geese. Artemisia annua can be further developed as a 
      feed additive.
CI  - Copyright (c) 2024 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Cui, Yizhe
AU  - Cui Y
AD  - College of Animal Science and Technology, Heilongjiang Bayi Agricultural 
      University, Daqing, Heilongjiang 163319, China; Key Laboratory of Exploration and 
      Innovative Utilization of White Goose Germplasm Resources in the Cold Region of 
      Heilongjiang Province, Daqing, Heilongjiang 163319, China.
FAU - Leng, Xinyang
AU  - Leng X
AD  - College of Animal Science and Technology, Heilongjiang Bayi Agricultural 
      University, Daqing, Heilongjiang 163319, China; Key Laboratory of Exploration and 
      Innovative Utilization of White Goose Germplasm Resources in the Cold Region of 
      Heilongjiang Province, Daqing, Heilongjiang 163319, China.
FAU - Zhao, Yujie
AU  - Zhao Y
AD  - College of Animal Science and Technology, Heilongjiang Bayi Agricultural 
      University, Daqing, Heilongjiang 163319, China; Key Laboratory of Exploration and 
      Innovative Utilization of White Goose Germplasm Resources in the Cold Region of 
      Heilongjiang Province, Daqing, Heilongjiang 163319, China.
FAU - Zhao, Yu
AU  - Zhao Y
AD  - College of Animal Science and Technology, Heilongjiang Bayi Agricultural 
      University, Daqing, Heilongjiang 163319, China; Key Laboratory of Exploration and 
      Innovative Utilization of White Goose Germplasm Resources in the Cold Region of 
      Heilongjiang Province, Daqing, Heilongjiang 163319, China.
FAU - Wang, Qiuju
AU  - Wang Q
AD  - College of Animal Science and Technology, Heilongjiang Bayi Agricultural 
      University, Daqing, Heilongjiang 163319, China; Key Laboratory of Exploration and 
      Innovative Utilization of White Goose Germplasm Resources in the Cold Region of 
      Heilongjiang Province, Daqing, Heilongjiang 163319, China. Electronic address: 
      Wqj_9@126.com.
LA  - eng
PT  - Journal Article
DEP - 20240228
PL  - England
TA  - Poult Sci
JT  - Poultry science
JID - 0401150
RN  - 0 (Antioxidants)
SB  - IM
MH  - Animals
MH  - *Gastrointestinal Microbiome/drug effects
MH  - *Artemisia annua/chemistry
MH  - *Geese/growth & development/physiology
MH  - *Animal Feed/analysis
MH  - Male
MH  - *Diet/veterinary
MH  - *Antioxidants/metabolism
MH  - *Dietary Supplements/analysis
MH  - *Random Allocation
MH  - Animal Nutritional Physiological Phenomena/drug effects
PMC - PMC10950859
OTO - NOTNLM
OT  - antioxidant activity
OT  - goose
OT  - immunity
OT  - intestinal microbiota
EDAT- 2024/03/14 00:42
MHDA- 2024/04/30 06:45
PMCR- 2024/02/28
CRDT- 2024/03/13 19:04
PHST- 2024/01/14 00:00 [received]
PHST- 2024/02/18 00:00 [revised]
PHST- 2024/02/22 00:00 [accepted]
PHST- 2024/04/30 06:45 [medline]
PHST- 2024/03/14 00:42 [pubmed]
PHST- 2024/03/13 19:04 [entrez]
PHST- 2024/02/28 00:00 [pmc-release]
AID - S0032-5791(24)00173-1 [pii]
AID - 103594 [pii]
AID - 10.1016/j.psj.2024.103594 [doi]
PST - ppublish
SO  - Poult Sci. 2024 May;103(5):103594. doi: 10.1016/j.psj.2024.103594. Epub 2024 Feb 
      28.