PMID- 38491834
OWN - NLM
STAT- Publisher
LR  - 20240316
IS  - 1558-9455 (Electronic)
IS  - 1558-9447 (Linking)
DP  - 2024 Mar 16
TI  - Estimating the Minimal Clinically Important Difference on the Visual Analogue 
      Scale for Carpometacarpal Thumb Joint Osteoarthritis.
PG  - 15589447241235344
LID - 10.1177/15589447241235344 [doi]
AB  - BACKGROUND: The minimal clinically important difference (MCID) is the smallest 
      perceived treatment effect that patients deem clinically significant. There is 
      currently no agreement on an appropriate MCID for the pain visual analogue scale 
      (VAS) in the context of thumb osteoarthritis (OA). METHODS: We approximated MCIDs 
      using a distribution-based approach that pooled standard deviations (SDs) 
      associated with baseline mean values of the pain VAS (0-100 mm). We extracted the 
      data from randomized controlled trials (RCTs) included in a systematic review of 
      adults with long-term OA of the thumb. We excluded RCTs that did not report 
      baseline SD values. The MCIDs were derived at 0.4 and 0.5 SDs of the pooled SD 
      and compared with previously published MCIDs for the pain VAS in OA. RESULTS: A 
      total of 403 patients were pooled from 7 RCTs for the analysis. The mean baseline 
      VAS pain score was 5.6 cm. We derived an MCID of 0.72 cm at 0.4 SDs and 0.91 cm 
      at 0.5 SDs using baseline SDs. We found that MCIDs derived from a 
      distribution-based approach approximated published MCIDs for the VAS for pain for 
      OA in the knee and hip. CONCLUSION: The authors propose that a change of 0.7 to 
      0.9 cm on the VAS is clinically meaningful in the context of long-term OA of the 
      thumb.
FAU - Olaiya, Oluwatobi R
AU  - Olaiya OR
AUID- ORCID: 0000-0001-6632-9595
AD  - Division of Plastic Surgery, Department of Surgery, McMaster University, 
      Hamilton, ON, Canada.
AD  - Department of Health Research Methods, Evidence, and Impact, McMaster University, 
      Hamilton, ON, Canada.
FAU - Abraha, Beraki
AU  - Abraha B
AUID- ORCID: 0009-0003-5953-0700
AD  - Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
FAU - Gallo, Lucas
AU  - Gallo L
AD  - Division of Plastic Surgery, Department of Surgery, McMaster University, 
      Hamilton, ON, Canada.
AD  - Department of Health Research Methods, Evidence, and Impact, McMaster University, 
      Hamilton, ON, Canada.
FAU - Hircock, Caroline
AU  - Hircock C
AD  - Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, 
      Canada.
FAU - Huynh, Minh
AU  - Huynh M
AD  - Division of Plastic Surgery, Department of Surgery, McMaster University, 
      Hamilton, ON, Canada.
FAU - McRae, Matthew
AU  - McRae M
AD  - Division of Plastic Surgery, Department of Surgery, McMaster University, 
      Hamilton, ON, Canada.
LA  - eng
PT  - Journal Article
DEP - 20240316
PL  - United States
TA  - Hand (N Y)
JT  - Hand (New York, N.Y.)
JID - 101264149
SB  - IM
OTO - NOTNLM
OT  - MCID
OT  - distribution-based methods
OT  - patient-reported outcomes
OT  - thumb osteoarthritis
OT  - visual analogue scale
COIS- Declaration of Conflicting InterestsThe author(s) declared no potential conflicts 
      of interest with respect to the research, authorship, and/or publication of this 
      article.
EDAT- 2024/03/16 21:43
MHDA- 2024/03/16 21:43
CRDT- 2024/03/16 04:33
PHST- 2024/03/16 21:43 [medline]
PHST- 2024/03/16 21:43 [pubmed]
PHST- 2024/03/16 04:33 [entrez]
AID - 10.1177/15589447241235344 [doi]
PST - aheadofprint
SO  - Hand (N Y). 2024 Mar 16:15589447241235344. doi: 10.1177/15589447241235344.