PMID- 38492479
OWN - NLM
STAT- MEDLINE
DCOM- 20240408
LR  - 20240408
IS  - 1879-2448 (Electronic)
IS  - 0043-1354 (Linking)
VI  - 254
DP  - 2024 May 1
TI  - Anaerobic biotransformation of hexachlorocyclohexane isomers in aqueous 
      condition: Dual CCl isotope fractionation and impact on microbial community 
      compositions.
PG  - 121389
LID - S0043-1354(24)00291-4 [pii]
LID - 10.1016/j.watres.2024.121389 [doi]
AB  - Hexachlorocyclohexane (HCH) isomers are persistent organic pollutants (POPs) with 
      high toxicity, lipid solubility, chemical stability. Despite the current ban on 
      usage of Lindane, residual contamination cannot be ignored, and HCH are 
      frequently detected in groundwater and threaten human health. Cultures capable of 
      degrading alpha-HCH, beta-HCH, gamma-HCH, and delta-HCH individually have been enriched in 
      anoxic aqueous conditions. Compound-Specific Isotope Analysis (CSIA) was applied 
      to examine the transformation mechanisms of different HCH isomers by the four 
      enrichment cultures. 16S rRNA sequencing techniques were employed to examine the 
      community composition of the enrichment cultures and detect changes in these 
      communities resulting from adding individual HCH isomers. The results indicated 
      that the ability of the enrichment cultures for dichloroelimination of HCH 
      isomers was inconsistent. During dichloroelimination, different bond cleavage 
      mode of beta- and delta-HCH led to distinct isotopic effects. HCH isomers had 
      significant impact on the microbial community, while different microbial 
      communities showed comparable isotopic effects during the transformation of a 
      specific HCH isomer. In addition, bacteria in the phyla Proteobacteria and 
      Firmicutes were proposed as the dominant dechlorinators. This study provides a 
      novel perspective on the mode of bond cleavage during HCH dichloroelimination and 
      the effect of HCH on microbial communities, which could potentially support the 
      evaluation of HCH transformation by CSIA and their effects on the microecosystems 
      of groundwater.
CI  - Copyright (c) 2024 Elsevier Ltd. All rights reserved.
FAU - Zhang, Xinyu
AU  - Zhang X
AD  - College of Light Industry and Food Engineering, Guangxi University, Daxue Road 
      100, Nanning 530004, China.
FAU - Zheng, Yan
AU  - Zheng Y
AD  - College of Food and Biological Engineering, Zhengzhou University of Light 
      Industry, Zhengzhou 450002, China.
FAU - Su, Ziming
AU  - Su Z
AD  - School of Resources, Environment and Materials, Guangxi University, Daxue Road 
      100, Nanning 530004, China.
FAU - Wang, Zhenyu
AU  - Wang Z
AD  - Department of Technical Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318, Leipzig, Germany.
FAU - Zhang, Jian
AU  - Zhang J
AD  - College of Light Industry and Food Engineering, Guangxi University, Daxue Road 
      100, Nanning 530004, China.
FAU - Jia, Zhongjun
AU  - Jia Z
AD  - State Key Laboratory of Soil and Sustainable Agriculture, Institute of Soil 
      Science, Chinese Academy of Sciences, Nanjing, 210008, China.
FAU - Kummel, Steffen
AU  - Kummel S
AD  - Department of Technical Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318, Leipzig, Germany.
FAU - Qin, Chengrong
AU  - Qin C
AD  - College of Light Industry and Food Engineering, Guangxi University, Daxue Road 
      100, Nanning 530004, China. Electronic address: qin_chengrong@163.com.
FAU - Liu, Yaqing
AU  - Liu Y
AD  - College of Light Industry and Food Engineering, Guangxi University, Daxue Road 
      100, Nanning 530004, China. Electronic address: yaqing.liu@gxu.edu.cn.
FAU - Wang, Shuangfei
AU  - Wang S
AD  - College of Light Industry and Food Engineering, Guangxi University, Daxue Road 
      100, Nanning 530004, China.
FAU - Nijenhuis, Ivonne
AU  - Nijenhuis I
AD  - Department of Technical Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318, Leipzig, Germany.
FAU - Richnow, Hans H
AU  - Richnow HH
AD  - Department of Technical Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318, Leipzig, Germany; Isodetect, Deutscher 
      Platz 5b, 04103 Leipzig, Germany.
LA  - eng
PT  - Journal Article
DEP - 20240227
PL  - England
TA  - Water Res
JT  - Water research
JID - 0105072
RN  - 319-86-8 (delta-hexachlorocyclohexane)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
RN  - 0 (Carbon Isotopes)
RN  - 0 (RNA, Ribosomal, 16S)
SB  - IM
MH  - Humans
MH  - *Hexachlorocyclohexane/chemistry
MH  - Biodegradation, Environmental
MH  - Carbon Isotopes/analysis
MH  - Anaerobiosis
MH  - RNA, Ribosomal, 16S/genetics/metabolism
MH  - Biotransformation
MH  - *Microbiota
OTO - NOTNLM
OT  - 16S rRNA sequencing
OT  - Dichloroelimination
OT  - Multi-isotope fractionation
OT  - Organochlorine pesticide
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2024/03/17 00:42
MHDA- 2024/04/08 06:43
CRDT- 2024/03/16 19:10
PHST- 2023/12/19 00:00 [received]
PHST- 2024/02/18 00:00 [revised]
PHST- 2024/02/26 00:00 [accepted]
PHST- 2024/04/08 06:43 [medline]
PHST- 2024/03/17 00:42 [pubmed]
PHST- 2024/03/16 19:10 [entrez]
AID - S0043-1354(24)00291-4 [pii]
AID - 10.1016/j.watres.2024.121389 [doi]
PST - ppublish
SO  - Water Res. 2024 May 1;254:121389. doi: 10.1016/j.watres.2024.121389. Epub 2024 
      Feb 27.