PMID- 38494031
OWN - NLM
STAT- MEDLINE
DCOM- 20240401
LR  - 20240401
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 925
DP  - 2024 May 15
TI  - Emerging and legacy contaminants on the Brazilian southern coast (Santa 
      Catarina): A multi-biomarker approach in oysters Crassostrea gasar (Adanson, 
      1757).
PG  - 171679
LID - S0048-9697(24)01821-7 [pii]
LID - 10.1016/j.scitotenv.2024.171679 [doi]
AB  - Coastal environments, such as those in the Santa Catarina State (SC, Brazil), are 
      considered the primary receptors of anthropogenic pollutants. In this study, our 
      objective was to evaluate the levels of emerging contaminants (ECs) and 
      persistent organic pollutants (POPs) in indigenous Crassostrea gasar oysters from 
      different regions of SC coast in the summer season (March 2022). Field 
      collections were conducted in the Sao Francisco do Sul, Itajai, Florianopolis and 
      Laguna coastal zones. We analyzed the bioaccumulation levels of 75 compounds, 
      including antibiotics (AB), endocrine disruptors (ED), non-steroidal 
      anti-inflammatory drugs (NSAIDs), polycyclic aromatic hydrocarbons (PAHs), 
      polychlorinated biphenyls (PCBs) and pesticides. Furthermore, we assessed 
      biomarker responses related to biotransformation, antioxidant defense, heat shock 
      protection and oxidative damage in oysters' gills. Prevalence of ECs was observed 
      in the central and southern regions, while the highest concentrations of POPs 
      were detected in the central-northern regions of SC. Oysters exhibited an 
      induction in biotransformation systems (cyp2au1 and cyp356a1, sult and GST 
      activity) and antioxidant enzymes activities (SOD, CAT and GPx). Higher 
      susceptibility to lipid peroxidation was observed in the animals from 
      Florianopolis compared to other regions. Correlation analyses indicated possible 
      associations between contaminants and environmental variables in the biomarker 
      responses, serving as a warning related to climate change. Our results highlight 
      the influence of anthropogenic activities on SC, serving as baseline of ECs and 
      POPs levels in the coastal areas of Santa Catarina, indicating more critical 
      zones for extensive monitoring, aiming to conserve coastal regions.
CI  - Copyright (c) 2024 Elsevier B.V. All rights reserved.
FAU - Bastolla, Camila L V
AU  - Bastolla CLV
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Guerreiro, Fernando C
AU  - Guerreiro FC
AD  - Department of Natural Sciences, Blumenau Regional University Foundation, FURB, 
      Blumenau, Santa Catarina, Brazil.
FAU - Saldana-Serrano, Miguel
AU  - Saldana-Serrano M
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Gomes, Carlos H A M
AU  - Gomes CHAM
AD  - Marine Mollusc Laboratory (LMM), Department of Aquaculture, Center for 
      Agricultural Sciences, Federal University of Santa Catarina, UFSC, Florianopolis, 
      Santa Catarina, Brazil.
FAU - Lima, Daina
AU  - Lima D
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Rutkoski, Camila F
AU  - Rutkoski CF
AD  - Department of Natural Sciences, Blumenau Regional University Foundation, FURB, 
      Blumenau, Santa Catarina, Brazil.
FAU - Mattos, Jaco J
AU  - Mattos JJ
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Dias, Vera Helena V
AU  - Dias VHV
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Righetti, Barbara P H
AU  - Righetti BPH
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Ferreira, Clarissa P
AU  - Ferreira CP
AD  - Department of Fisheries Engineering and Biological Sciences, State University of 
      Santa Catarina, UDESC, Laguna, Brazil.
FAU - Martim, Julia
AU  - Martim J
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Alves, Thiago C
AU  - Alves TC
AD  - Department of Natural Sciences, Blumenau Regional University Foundation, FURB, 
      Blumenau, Santa Catarina, Brazil.
FAU - Melo, Claudio M R
AU  - Melo CMR
AD  - Department of Fisheries Engineering and Biological Sciences, State University of 
      Santa Catarina, UDESC, Laguna, Brazil.
FAU - Marques, Maria R F
AU  - Marques MRF
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil.
FAU - Luchmann, Karim H
AU  - Luchmann KH
AD  - Department of Fisheries Engineering and Biological Sciences, State University of 
      Santa Catarina, UDESC, Laguna, Brazil.
FAU - Almeida, Eduardo A
AU  - Almeida EA
AD  - Department of Natural Sciences, Blumenau Regional University Foundation, FURB, 
      Blumenau, Santa Catarina, Brazil.
FAU - Bainy, Afonso C D
AU  - Bainy ACD
AD  - Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry (LABCAI), 
      Center for Biological Sciences, Federal University of Santa Catarina (UFSC), 
      Florianopolis, Santa Catarina, Brazil. Electronic address: afonso.bainy@ufsc.br.
LA  - eng
PT  - Journal Article
DEP - 20240316
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - 0 (Antioxidants)
RN  - 0 (Biomarkers)
RN  - 0 (Polycyclic Aromatic Hydrocarbons)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - *Crassostrea/physiology
MH  - Brazil
MH  - Antioxidants/analysis
MH  - Biomarkers/metabolism
MH  - *Polycyclic Aromatic Hydrocarbons/analysis
MH  - *Water Pollutants, Chemical/analysis
MH  - Environmental Monitoring/methods
OTO - NOTNLM
OT  - Aquatic pollution
OT  - Biotransformation
OT  - Mariculture
OT  - Oxidative stress
OT  - POPs
OT  - Pharmaceutical compounds
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationship that could have appeared 
      to influence the work reported in this paper.
EDAT- 2024/03/18 00:42
MHDA- 2024/04/01 06:43
CRDT- 2024/03/17 20:29
PHST- 2023/11/25 00:00 [received]
PHST- 2024/03/06 00:00 [revised]
PHST- 2024/03/10 00:00 [accepted]
PHST- 2024/04/01 06:43 [medline]
PHST- 2024/03/18 00:42 [pubmed]
PHST- 2024/03/17 20:29 [entrez]
AID - S0048-9697(24)01821-7 [pii]
AID - 10.1016/j.scitotenv.2024.171679 [doi]
PST - ppublish
SO  - Sci Total Environ. 2024 May 15;925:171679. doi: 10.1016/j.scitotenv.2024.171679. 
      Epub 2024 Mar 16.