PMID- 38497051
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240319
IS  - 2296-4185 (Print)
IS  - 2296-4185 (Electronic)
IS  - 2296-4185 (Linking)
VI  - 12
DP  - 2024
TI  - Cancer diagnosis and treatment platform based on manganese-based nanomaterials.
PG  - 1363569
LID - 10.3389/fbioe.2024.1363569 [doi]
LID - 1363569
AB  - Cancer is a leading cause of death worldwide, and the development of new 
      diagnostic and treatment methods is crucial. Manganese-based nanomaterials 
      (MnNMs) have emerged as a focal point in the field of cancer diagnosis and 
      treatment due to their multifunctional properties. These nanomaterials have been 
      extensively explored as contrast agents for various imaging technologies such as 
      magnetic resonance imaging (MRI), photoacoustic imaging (PAI), and near-infrared 
      fluorescence imaging (NIR-FL). The use of these nanomaterials has significantly 
      enhanced the contrast for precise tumor detection and localization. Moreover, 
      MnNMs have shown responsiveness to the tumor microenvironment (TME), enabling 
      innovative approaches to cancer treatment. This review provides an overview of 
      the latest developments of MnNMs and their potential applications in tumor 
      diagnosis and therapy. Finally, potential challenges and prospects of MnNMs in 
      clinical applications are discussed. We believe that this review would serve as a 
      valuable resource for guiding further research on the application of manganese 
      nanomaterials in cancer diagnosis and treatment, addressing the current 
      limitations, and proposing future research directions.
CI  - Copyright (c) 2024 Fei, Liu, Zeng, Yang, Chen, Duan, Lu and Chen.
FAU - Fei, Jia
AU  - Fei J
AD  - Zhuhai Clinical Medical College of Jinan University (Zhuhai People's Hospital), 
      Zhuhai, China.
FAU - Liu, Yanyan
AU  - Liu Y
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
FAU - Zeng, Ya
AU  - Zeng Y
AD  - Zhuhai Clinical Medical College of Jinan University (Zhuhai People's Hospital), 
      Zhuhai, China.
FAU - Yang, Mingqi
AU  - Yang M
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
FAU - Chen, Shanshan
AU  - Chen S
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
FAU - Duan, Xiaobing
AU  - Duan X
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
FAU - Lu, Ligong
AU  - Lu L
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
FAU - Chen, Muhe
AU  - Chen M
AD  - Guangdong Provincial Key Laboratory of Tumor Interventional Diagnosis and 
      Treatment, Zhuhai Institute of Translational Medicine, Zhuhai Clinical Medical 
      College of Jinan University, Zhuhai, Guangdong, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20240301
PL  - Switzerland
TA  - Front Bioeng Biotechnol
JT  - Frontiers in bioengineering and biotechnology
JID - 101632513
PMC - PMC10940866
OTO - NOTNLM
OT  - TME (tumor microenvironment)
OT  - cancer diagnosis
OT  - cancer treatment
OT  - manganese nanomaterials
OT  - nanomaterials
OT  - tumor
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2024/03/18 06:43
MHDA- 2024/03/18 06:44
PMCR- 2024/01/01
CRDT- 2024/03/18 04:45
PHST- 2023/12/31 00:00 [received]
PHST- 2024/01/29 00:00 [accepted]
PHST- 2024/03/18 06:44 [medline]
PHST- 2024/03/18 06:43 [pubmed]
PHST- 2024/03/18 04:45 [entrez]
PHST- 2024/01/01 00:00 [pmc-release]
AID - 1363569 [pii]
AID - 10.3389/fbioe.2024.1363569 [doi]
PST - epublish
SO  - Front Bioeng Biotechnol. 2024 Mar 1;12:1363569. doi: 10.3389/fbioe.2024.1363569. 
      eCollection 2024.