PMID- 38497216
OWN - NLM
STAT- MEDLINE
DCOM- 20240515
LR  - 20240517
IS  - 1552-5279 (Electronic)
IS  - 1552-5260 (Print)
IS  - 1552-5260 (Linking)
VI  - 20
IP  - 5
DP  - 2024 May
TI  - Wrist-worn actigraphy in agitated late-stage dementia patients: A feasibility 
      study on digital inclusion.
PG  - 3211-3218
LID - 10.1002/alz.13772 [doi]
AB  - BACKGROUND: Wrist-worn actigraphy can be an objective tool to assess sleep and 
      other behavioral and psychological symptoms in dementia (BPSD). We investigated 
      the feasibility of using wearable actigraphy in agitated late-stage dementia 
      patients. METHODS: Agitated, late-stage Alzheimer's dementia care home residents 
      in Greater London area (n = 29; 14 females, mean age +/- SD: 80.8 +/- 8.2; 93.1% 
      White) were recruited to wear an actigraphy watch for 4 weeks. Wearing time was 
      extracted to evaluate compliance, and factors influencing compliance were 
      explored. RESULTS: A high watch-acceptance (96.6%) and compliance rate (88.0%) 
      was noted. Non-compliance was not associated with age or BPSD symptomatology. 
      However, participants with "better" cognitive function (R = 0.42, p = 0.022) and 
      during nightshift (F(1.240, 33.475 )= 8.075, p = 0.005) were less compliant. 
      Female participants were also marginally less compliant (F(1, 26 )= 3.790, 
      p = 0.062). DISCUSSIONS: Wrist-worn actigraphy appears acceptable and feasible in 
      late-stage agitated dementia patients. Accommodating the needs of both the 
      patients and their carers may further improve compliance.
CI  - (c) 2024 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on 
      behalf of Alzheimer's Association.
FAU - Guu, Ta-Wei
AU  - Guu TW
AUID- ORCID: 0000-0002-2621-0781
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
AD  - Division of Psychiatry, Departments of Internal Medicine, China Medical 
      University Beigang Hospital, Yunlin, Taiwan.
AD  - Sleep Medicine Center and Mind-Body Interface Laboratory (MBI-Lab), China Medical 
      University Hospital, Taichung, Taiwan.
FAU - Brem, Anna-Katharine
AU  - Brem AK
AUID- ORCID: 0000-0003-0295-6834
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
AD  - University Hospital of Old Age Psychiatry, University of Bern, Bern, Switzerland.
FAU - Albertyn, Christopher P
AU  - Albertyn CP
AUID- ORCID: 0000-0002-4682-6890
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
FAU - Kandangwa, Pooja
AU  - Kandangwa P
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
FAU - Aarsland, Dag
AU  - Aarsland D
AUID- ORCID: 0000-0001-6314-216X
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
AD  - Centre for Age-Related Medicine, Stavanger University Hospital, Stavanger, 
      Norway.
AD  - National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre 
      (BRC) at South London and Maudsley NHS Foundation Trust, London, UK.
FAU - Ffytche, Dominic
AU  - Ffytche D
AUID- ORCID: 0000-0002-4214-9642
AD  - Department of Old Age Psychiatry, Institute of Psychiatry, Psychology and 
      Neuroscience, King's College London, London, UK.
AD  - National Institute for Health Research (NIHR) Maudsley Biomedical Research Centre 
      (BRC) at South London and Maudsley NHS Foundation Trust, London, UK.
LA  - eng
GR  - 207711/Alzheimer's Research UK/
GR  - SC041156/Alzheimer's Research UK/
GR  - Global Clinical Trials Fund (GCTF)/
GR  - National Institute for Health Research (NIHR)/
GR  - Maudsley NHS Foundation Trust/
GR  - King's College London/
PT  - Journal Article
DEP - 20240318
PL  - United States
TA  - Alzheimers Dement
JT  - Alzheimer's & dementia : the journal of the Alzheimer's Association
JID - 101231978
SB  - IM
MH  - Humans
MH  - Female
MH  - *Actigraphy/methods/instrumentation
MH  - *Feasibility Studies
MH  - Male
MH  - *Wrist
MH  - Aged, 80 and over
MH  - *Dementia/diagnosis
MH  - Psychomotor Agitation/diagnosis
MH  - Aged
MH  - Wearable Electronic Devices
MH  - Patient Compliance
MH  - London
MH  - Sleep/physiology
PMC - PMC11095432
OTO - NOTNLM
OT  - Actigraphy
OT  - BPSD
OT  - compliance
OT  - dementia
OT  - feasibility
COIS- The authors declare no conflicts of interest. Author disclosures are available in 
      the Supporting information.
EDAT- 2024/03/18 06:42
MHDA- 2024/05/15 12:45
PMCR- 2024/03/18
CRDT- 2024/03/18 05:04
PHST- 2024/01/23 00:00 [received]
PHST- 2024/02/06 00:00 [accepted]
PHST- 2024/05/15 12:45 [medline]
PHST- 2024/03/18 06:42 [pubmed]
PHST- 2024/03/18 05:04 [entrez]
PHST- 2024/03/18 00:00 [pmc-release]
AID - ALZ13772 [pii]
AID - 10.1002/alz.13772 [doi]
PST - ppublish
SO  - Alzheimers Dement. 2024 May;20(5):3211-3218. doi: 10.1002/alz.13772. Epub 2024 
      Mar 18.