PMID- 38497859
OWN - NLM
STAT- MEDLINE
DCOM- 20240319
LR  - 20240319
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 28
IP  - 5
DP  - 2024 Mar
TI  - Effects of transcranial direct current stimulation combined with tinnitus 
      retraining therapy on sleep disorders in patients with chronic tinnitus.
PG  - 1768-1776
LID - 35590 [pii]
LID - 10.26355/eurrev_202403_35590 [doi]
AB  - OBJECTIVE: The aim of this study was to investigate the effects of transcranial 
      direct current stimulation (TDCS) combined with tinnitus retraining therapy (TRT) 
      on clinical efficacy and sleep disorder in patients with chronic tinnitus. 
      PATIENTS AND METHODS: 126 patients with chronic tinnitus treated in our hospital 
      from May 2020 to June 2022 were retrospectively analyzed. These subjects were 
      randomly divided into two groups: the electrical stimulation group and the 
      combined group, in line with the random table method, with 63 patients in each 
      group. Patients in the electrical stimulation group received TDCS treatment, and 
      patients in the combined group were given TDCS combined with TRT. The clinical 
      effects, tinnitus severity [Tinnitus Evaluation Questionnaire (TEQ) score and 
      Tinnitus handicap inventory (THI) score], sleep status [Sleep Status Rating Scale 
      (SRSS) score and Pittsburgh Sleep Quality Index (PSQI) score], psychological 
      status [Hamilton Anxiety Scale (HAMA) score and Self Rating Depression Scale 
      (SDS) score] and the quality of life (Quality of Life Scale) of these subjects in 
      two groups were analyzed. RESULTS: The clinical effect of simple TDCS was 82.53%, 
      which was sharply lower compared to 95.24% in the combined group (p<0.05). After 
      the treatment, TEQ score, THI score, SRSS score, PSQI score, HAMA score, and SDS 
      score were decreased in both groups (p<0.05), and the combined group was much 
      lower than the TDCS group (p<0.01). Compared with the pre-treatment period, the 
      scores of restrictions in daily living, medical resource utilization, somatic 
      symptoms, and emotional disturbance were elevated in both groups after treatment, 
      and the combined group had markedly higher scores than the TDCS group (p<0.05). 
      CONCLUSIONS: TDCS combined with TRT had obvious effects in treating chronic 
      tinnitus, which largely reduced the severity of tinnitus, improved patients' 
      sleep quality and psychological status, and improved the quality of life, 
      indicating a certain worthy of clinical application and promotion.
FAU - Jia, X-D
AU  - Jia XD
AD  - Department of Otolaryngology, Henan Provincial People's Hospital, People's 
      Hospital of Zhengzhou University, Zhengzhou, Henan, China. syent5397@zzu.edu.cn.
FAU - Li, Y-K
AU  - Li YK
FAU - Xie, C-C
AU  - Xie CC
FAU - Ding, X-L
AU  - Ding XL
FAU - Ding, S-G
AU  - Ding SG
FAU - Liu, H-J
AU  - Liu HJ
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
SB  - IM
MH  - Humans
MH  - *Transcranial Direct Current Stimulation
MH  - Quality of Life
MH  - Retrospective Studies
MH  - *Tinnitus/therapy
MH  - *Sleep Wake Disorders/therapy
EDAT- 2024/03/18 12:46
MHDA- 2024/03/19 06:44
CRDT- 2024/03/18 11:14
PHST- 2024/03/19 06:44 [medline]
PHST- 2024/03/18 12:46 [pubmed]
PHST- 2024/03/18 11:14 [entrez]
AID - 35590 [pii]
AID - 10.26355/eurrev_202403_35590 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2024 Mar;28(5):1768-1776. doi: 
      10.26355/eurrev_202403_35590.