PMID- 38499935 OWN - NLM STAT- Publisher LR - 20240319 IS - 1720-8386 (Electronic) IS - 0391-4097 (Linking) DP - 2024 Mar 18 TI - Relationship between diabetic peripheral neuropathy and adherence to the Mediterranean diet in patients with type 2 diabetes mellitus: an observational study. LID - 10.1007/s40618-024-02341-2 [doi] AB - PURPOSE: The main study goal is to assess the relationship between adherence to the mediterranean diet (MD) and the presence of diabetic peripheral neuropathy (DPN) in patients with type 2 diabetes mellitus (T2DM). METHODS: Observational pilot study of 174 patients diagnosed with T2DM. Sociodemographic and anthropometric variables, physical activity, smoking habits, blood biochemical parameters and comorbidities were recorded. The presence of alterations in sensitivity to pressure, pain, thermal and vibration was explored. Good MD adherence was a score >/= 9 the 14-point MD adherence questionnaire (MEDAS-14). RESULTS: The study population consisted of 174 patients (61.5% men and 38.5% women), with a mean age of 69.56 +/- 8.86 years; 19% of these patients adhered to the MD. The score obtained in the MEDAS-14 was higher in patients who did not present alterations in sensitivity to pressure (p = 0.047) or vibration (p = 0.021). The patients without diabetic peripheral neuropathy were more likely to comply with the MD and had a higher score on the MEDAS-14 (p = 0.047). However, multivariate analysis showed that only altered sensitivity to pressure was associated with adherence to the MD (altered sensitivity OR = 2.9; 95%CI 1.02-8.22; p = 0.045). CONCLUSIONS: Although the patients with DPN had lower scores on the MEDAS questionnaire and therefore poorer adherence to the mediterranean diet, the only parameter significantly associated with the MD was that of sensitivity to pressure (monofilament test). CI - (c) 2024. The Author(s). FAU - Zunica-Garcia, S AU - Zunica-Garcia S AUID- ORCID: 0000-0001-6657-7636 AD - Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine, Miguel Hernandez University, Ctra N332, Km 87, 03550, San Juan de Alicante, Alicante, CP, Spain. szunica@umh.es. FAU - Blanquer-Gregori, J J AU - Blanquer-Gregori JJ AUID- ORCID: 0000-0003-2183-4840 AD - Faculty of Medicine, Miguel Hernandez University, Alicante, Spain. FAU - Sanchez-Ortiga, R AU - Sanchez-Ortiga R AUID- ORCID: 0000-0002-0117-960X AD - Endocrinology and Nutrition Department, Dr. Balmis General University Hospital, Alicante, Spain. FAU - Jimenez-Trujillo, M I AU - Jimenez-Trujillo MI AUID- ORCID: 0000-0002-9394-6799 AD - Department of Medicine and Surgery, Psychology, Preventive Medicine and Public Health and Medical Microbiology and Immunology, Nursing and Stomatology, Faculty of Health Sciences, Rey Juan Carlos University, Madrid, Spain. FAU - Chicharro-Luna, E AU - Chicharro-Luna E AUID- ORCID: 0000-0003-4766-5723 AD - Department of Behavioural Sciences and Health, Nursing Area, Faculty of Medicine, Miguel Hernandez University, Ctra N332, Km 87, 03550, San Juan de Alicante, Alicante, CP, Spain. LA - eng PT - Journal Article DEP - 20240318 PL - Italy TA - J Endocrinol Invest JT - Journal of endocrinological investigation JID - 7806594 SB - IM OTO - NOTNLM OT - Diabetes mellitus type 2 OT - Mediterranean diet OT - Monofilament test OT - Peripheral neuropathy OT - Pressure sensitivity EDAT- 2024/03/19 06:43 MHDA- 2024/03/19 06:43 CRDT- 2024/03/19 00:39 PHST- 2023/12/19 00:00 [received] PHST- 2024/02/15 00:00 [accepted] PHST- 2024/03/19 06:43 [medline] PHST- 2024/03/19 06:43 [pubmed] PHST- 2024/03/19 00:39 [entrez] AID - 10.1007/s40618-024-02341-2 [pii] AID - 10.1007/s40618-024-02341-2 [doi] PST - aheadofprint SO - J Endocrinol Invest. 2024 Mar 18. doi: 10.1007/s40618-024-02341-2.