PMID- 38504879 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240321 IS - 1188-4169 (Print) IS - 1481-8531 (Electronic) IS - 1188-4169 (Linking) VI - 49 IP - 11-12 DP - 2023 Nov 1 TI - Establishing Pandemic Influenza Severity Assessment (PISA) parameters and thresholds for Canada's FluWatch program. PG - 487-493 LID - 10.14745/ccdr.v49i1112a04 [doi] AB - BACKGROUND: The World Health Organization (WHO) developed a structured framework to enable countries to rapidly assess the severity of an influenza pandemic. This framework, the Pandemic Influenza Severity Assessment (PISA), is intended to be performed weekly during seasonal epidemics so that assessing influenza severity during a pandemic can be done with greater ease and efficiency. OBJECTIVE: Using influenza surveillance indicators within Canada's FluWatch program from seasons 2014-2015 to 2018-2019, national PISA thresholds were developed and assessed against seasonal data for seasons 2019-2020 to June of 2022-2023. OUTCOMES: Canada developed thresholds for each required indicator (transmissibility, seriousness of disease and impact) for multiple WHO-recommended parameters. The thresholds were assessed against four seasons, and it was determined that there was a good agreement between the PISA assessments and the characterization of the season by FluWatch epidemiologists. CONCLUSION: With confidence in the validity of the PISA thresholds, the FluWatch program will begin to share PISA assessments weekly through the FluWatch report in the 2023-2024 seasons to help characterize influenza activity in Canada and inform responses to the seasonal influenza epidemic. CN - FluWatch Team1 LA - eng PT - Journal Article DEP - 20231101 PL - Canada TA - Can Commun Dis Rep JT - Canada communicable disease report = Releve des maladies transmissibles au Canada JID - 9303729 PMC - PMC10946583 OTO - NOTNLM OT - FluWatch OT - PISA OT - seasonal influenza OT - severity OT - thresholds COIS- Competing interests The authors have no competing interests. EDAT- 2024/03/20 06:45 MHDA- 2024/03/20 06:46 PMCR- 2023/11/01 CRDT- 2024/03/20 03:59 PHST- 2024/03/20 06:46 [medline] PHST- 2024/03/20 06:45 [pubmed] PHST- 2024/03/20 03:59 [entrez] PHST- 2023/11/01 00:00 [pmc-release] AID - 49111204 [pii] AID - 10.14745/ccdr.v49i1112a04 [doi] PST - epublish SO - Can Commun Dis Rep. 2023 Nov 1;49(11-12):487-493. doi: 10.14745/ccdr.v49i1112a04. eCollection 2023 Nov 1.