PMID- 38510610
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240322
IS  - 2772-5294 (Electronic)
IS  - 2772-5294 (Linking)
VI  - 4
DP  - 2024
TI  - Prospective insights into spinal surgery outcomes and adverse events: A 
      comparative study between patients 65-79 years vs. >/=80 years from a German 
      tertiary center.
PG  - 102768
LID - 10.1016/j.bas.2024.102768 [doi]
LID - 102768
AB  - INTRODUCTION: In light of an aging global population, understanding adverse 
      events (AEs) in surgeries for older adults is crucial for optimal outcomes and 
      patient safety. RESEARCH QUESTION: Our study compares surgical outcomes and AEs 
      in patients aged 65-79 with those aged >/=80, focusing on clinical outcomes, 
      morbidity and mortality rates, and age-related risk factors for AEs. MATERIAL AND 
      METHODS: Our study, from January 2019 to December 2022, involved patients aged 
      65-79 and >/= 80 undergoing spinal surgery. Each patient was evaluated for AEs 
      post-discharge, defined as negative clinical outcomes within 30 days 
      post-surgery. Patients were categorized based on primary spinal diagnoses: 
      degenerative, oncological, traumatic, and infectious. RESULTS: We enrolled 546 
      patients aged 65-79 and 184 octogenarians. Degenerative diseases were most common 
      in both groups, with higher infection and tumor rates in the younger cohort. 
      Octogenarians had a higher Charlson Comorbidity Index and longer ICU/hospital 
      stays. Surgery-related AE rates were 8.1% for 65-79-year-olds and 15.8% for 
      octogenarians, with mortality around 2% in both groups. DISCUSSION AND 
      CONCLUSION: Our prospective analysis shows octogenarians are more susceptible to 
      surgical AEs, linked to greater health complexities. Despite higher AEs in older 
      patients, low mortality rates across both age groups highlight the safety of 
      spinal surgery. Tracking AEs is crucial for patient communication and impacts 
      healthcare accreditation and funding.
CI  - (c) 2024 Published by Elsevier B.V. on behalf of EUROSPINE, the Spine Society of 
      Europe, EANS, the European Association of Neurosurgical Societies.
FAU - Lenga, Pavlina
AU  - Lenga P
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
FAU - Dao Trong, Philip
AU  - Dao Trong P
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
FAU - Papakonstantinou, Vassilios
AU  - Papakonstantinou V
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
FAU - Unterberg, Andreas W
AU  - Unterberg AW
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
FAU - Krieg, Sandro M
AU  - Krieg SM
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
FAU - Ishak, Basem
AU  - Ishak B
AD  - Department of Neurosurgery, Heidelberg University Hospital, Heidelberg, Germany.
LA  - eng
PT  - Journal Article
DEP - 20240217
PL  - Netherlands
TA  - Brain Spine
JT  - Brain & spine
JID - 9918470888906676
PMC - PMC10951790
OTO - NOTNLM
OT  - Adverse events
OT  - Aging population
OT  - Spine surgery
COIS- The authors have no relevant financial or non-financial interests to disclose.
EDAT- 2024/03/21 06:43
MHDA- 2024/03/21 06:44
PMCR- 2024/02/17
CRDT- 2024/03/21 04:13
PHST- 2023/12/16 00:00 [received]
PHST- 2024/01/18 00:00 [revised]
PHST- 2024/02/14 00:00 [accepted]
PHST- 2024/03/21 06:44 [medline]
PHST- 2024/03/21 06:43 [pubmed]
PHST- 2024/03/21 04:13 [entrez]
PHST- 2024/02/17 00:00 [pmc-release]
AID - S2772-5294(24)00024-9 [pii]
AID - 102768 [pii]
AID - 10.1016/j.bas.2024.102768 [doi]
PST - epublish
SO  - Brain Spine. 2024 Feb 17;4:102768. doi: 10.1016/j.bas.2024.102768. eCollection 
      2024.