PMID- 38510893
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240322
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 16
IP  - 2
DP  - 2024 Feb
TI  - Hepatic Angiomyolipoma With Predominant Lipomatous Component: A Rare Entity.
PG  - e54357
LID - 10.7759/cureus.54357 [doi]
LID - e54357
AB  - Hepatic angiomyolipoma (HAML) is a rare benign mesenchymal tumor with varying 
      amounts of mature adipose tissue, smooth muscle cells, and thick-walled blood 
      vessels. We present a rare case of hepatic angiomyolipoma (AML) with predominant 
      lipomatous components. A 42-year-old female presented to the hospital with pain 
      in the right lumbar region. On imaging, there was a large fat-predominant mass 
      attached to the surface of the liver extending down to the lumbar region. On 
      small biopsy, it was reported as a well-differentiated adipocytic neoplasm, and 
      fluorescence in situ hybridization (FISH) studies performed for MDM2 were 
      negative. On excision, histopathological examination showed predominantly fat 
      components, but there were few epithelioid cells between adipocytes and 
      thick-walled blood vessels. These cells were positive for Melan-A, HMB45, and 
      smooth muscle actin (SMA) and negative for hepatocyte paraffin-1 (Hep Par1). 
      Angiomyolipoma is a benign tumor and has a good prognosis with surgical excision. 
      Few cases are associated with tuberous sclerosis.
CI  - Copyright (c) 2024, Pervaiz et al.
FAU - Pervaiz, Jaweria Jr
AU  - Pervaiz J Jr
AD  - Department of Histopathology, Chughtai Institute of Pathology, Lahore, PAK.
FAU - Zaman, Samina
AU  - Zaman S
AD  - Department of Histopathology, Children's Hospital and Institute of Child Health, 
      Lahore, PAK.
FAU - Khalid, Sohaib
AU  - Khalid S
AD  - Department of Histopathology, Chughtai Institute of Pathology, Lahore, PAK.
FAU - Rafique, Zubaria
AU  - Rafique Z
AD  - Department of Histopathology, Chughtai Institute of Pathology, Lahore, PAK.
FAU - Noor, Rida
AU  - Noor R
AD  - Department of Pathology, Faisalabad Medical University, Faisalabad, PAK.
LA  - eng
PT  - Case Reports
DEP - 20240217
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC10951131
OTO - NOTNLM
OT  - angiomyolipoma
OT  - hepatic
OT  - lipomatous predominant
OT  - pecomas
OT  - rare entity
COIS- The authors have declared that no competing interests exist.
EDAT- 2024/03/21 06:43
MHDA- 2024/03/21 06:44
PMCR- 2024/02/17
CRDT- 2024/03/21 04:17
PHST- 2024/02/17 00:00 [accepted]
PHST- 2024/03/21 06:44 [medline]
PHST- 2024/03/21 06:43 [pubmed]
PHST- 2024/03/21 04:17 [entrez]
PHST- 2024/02/17 00:00 [pmc-release]
AID - 10.7759/cureus.54357 [doi]
PST - epublish
SO  - Cureus. 2024 Feb 17;16(2):e54357. doi: 10.7759/cureus.54357. eCollection 2024 
      Feb.