PMID- 38513442
OWN - NLM
STAT- MEDLINE
DCOM- 20240408
LR  - 20240408
IS  - 1873-3336 (Electronic)
IS  - 0304-3894 (Linking)
VI  - 469
DP  - 2024 May 5
TI  - Tracking the transformation of persistent organic pollutants in food webs using 
      multi element isotope and enantiomer fractionation.
PG  - 134046
LID - S0304-3894(24)00625-3 [pii]
LID - 10.1016/j.jhazmat.2024.134046 [doi]
AB  - In order to track the transformation of persistent organic pollutants (POPs) in 
      food webs, field experiments were conducted at two sites using stable isotope and 
      enantiomer fractionation concepts. The enantiomers of alpha-hexachlorocyclohexane 
      (alpha-HCH) were selected as representative compounds for POPs. Isotope and 
      enantiomer fractionation allowed the characterization of alpha-HCH enantiomer 
      biotransformation processes along trophic levels of the food web - from soil and 
      plants to animal livers, fat tissues and milk. The enrichment of heavy isotopes 
      in soils, plants and sediments as well as the changes of enantiomer fractionation 
      indicate that the biotransformation of alpha-HCH occurred in these compartments. 
      Moreover, the increase of carbon and chlorine isotopic compositions as well as 
      the changes of enantiomer fractionation of liver, fat tissues and milk 
      demonstrated that the overall HCH exposure was much higher than estimates based 
      on concentration levels, while the isotope and enantiomer fractionation revealed 
      the enantiomer specific enantiomer uptake across the blood-brain barriers. Dual 
      element isotope analysis suggested that complex transformation processes have 
      occurred along the potential food web from the HCH sources over different 
      environmental compartments to animal livers, fat tissues and milk. The results 
      imply that the analyses of stable isotope compositions and concentrations has 
      potential to reconstruct the exposure of higher organisms to POPs.
CI  - Copyright (c) 2024. Published by Elsevier B.V.
FAU - Liu, Xiao
AU  - Liu X
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Kummel, Steffen
AU  - Kummel S
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany.
FAU - Wu, Langping
AU  - Wu L
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany; Ecometrix Incorporated, 
      6800 Campobello Road, Mississauga, ON L5N 2L8, Canada; Isodetect GmbH, Deutscher 
      Platz 5b, 04103 Leipzig, Germany. Electronic address: lwu@ecometrix.ca.
FAU - Richnow, Hans H
AU  - Richnow HH
AD  - Department of Isotope Biogeochemistry, Helmholtz Centre for Environmental 
      Research-UFZ, Permoserstrasse 15, 04318 Leipzig, Germany; Isodetect GmbH, 
      Deutscher Platz 5b, 04103 Leipzig, Germany. Electronic address: 
      hans.richnow@ufz.de.
LA  - eng
PT  - Journal Article
DEP - 20240316
PL  - Netherlands
TA  - J Hazard Mater
JT  - Journal of hazardous materials
JID - 9422688
RN  - 319-84-6 (alpha-hexachlorocyclohexane)
RN  - 0 (Carbon Isotopes)
RN  - 0 (Persistent Organic Pollutants)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Soil)
RN  - 59NEE7PCAB (Hexachlorocyclohexane)
SB  - IM
MH  - Animals
MH  - Carbon Isotopes/analysis
MH  - *Persistent Organic Pollutants
MH  - Food Chain
MH  - Biodegradation, Environmental
MH  - *Environmental Pollutants/analysis
MH  - Soil
MH  - *Hexachlorocyclohexane
OTO - NOTNLM
OT  - Contaminated field
OT  - Food webs
OT  - Hexachlorocyclohexane
OT  - Higher organisms
OT  - Isotope fractionation
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2024/03/22 00:44
MHDA- 2024/04/08 06:43
CRDT- 2024/03/21 19:09
PHST- 2023/08/11 00:00 [received]
PHST- 2024/01/14 00:00 [revised]
PHST- 2024/03/13 00:00 [accepted]
PHST- 2024/04/08 06:43 [medline]
PHST- 2024/03/22 00:44 [pubmed]
PHST- 2024/03/21 19:09 [entrez]
AID - S0304-3894(24)00625-3 [pii]
AID - 10.1016/j.jhazmat.2024.134046 [doi]
PST - ppublish
SO  - J Hazard Mater. 2024 May 5;469:134046. doi: 10.1016/j.jhazmat.2024.134046. Epub 
      2024 Mar 16.