PMID- 38515812 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20240323 IS - 2766-3604 (Electronic) IS - 2766-3604 (Linking) VI - 2 IP - 1 DP - 2022 Mar TI - The Laterality of Age-related Hearing Loss and Cognition. PG - e008 LID - 10.1097/ONO.0000000000000008 [doi] AB - OBJECTIVES: To analyze the association between neurocognitive performance and age-related hearing loss in the right and left ear, individually. DESIGN: Subjects included 5277 participants (>/=50 years) from the general Hispanic population who underwent audiometric testing in a US multicentered epidemiologic study. Linear regression was performed to assess the cross-sectional association between cognitive performance (Digit Symbol Substitution Test [DSST], Word Frequency Test, Spanish-English Verbal Learning Test [SEVLT] 3 Trials, SEVLT Recall, and Six-Item Screener) and hearing in each ear (4-frequency pure-tone average), adjusting for age, sex, education, cardiovascular disease, and hearing aid use. RESULTS: Mean age was 58.4 +/- 6.2 years; 3254 (61.7%) were women. Mean pure-tone averages were 20.2 +/- 11.7 dB (right ear) and 20.2 +/- 12.3 dB (left ear). Multivariable regression demonstrated significant associations between all cognitive tests and hearing loss in both ears. CONCLUSIONS: Worsening hearing loss in the right and left ear was associated with decreased performance across all tests. No laterality in the association was demonstrated. CI - Copyright (c) 2022 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of Otology & Neurotology, Inc. FAU - Chern, Alexander AU - Chern A AD - Department of Otolaryngology-Head & Neck Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center and Columbia University Vagelos College of Physicians and Surgeons, New York, New York. AD - Department of Otolaryngology-Head & Neck Surgery, NewYork-Presbyterian/Weill Cornell Medical Center, New York, New York. FAU - Irace, Alexandria L AU - Irace AL AD - Department of Otolaryngology-Head & Neck Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center and Columbia University Vagelos College of Physicians and Surgeons, New York, New York. FAU - Golub, Justin S AU - Golub JS AD - Department of Otolaryngology-Head & Neck Surgery, NewYork-Presbyterian/Columbia University Irving Medical Center and Columbia University Vagelos College of Physicians and Surgeons, New York, New York. LA - eng PT - Journal Article DEP - 20220217 PL - United States TA - Otol Neurotol Open JT - Otology & neurotology open JID - 9918486785706676 PMC - PMC10950139 OTO - NOTNLM OT - Age OT - Cognition OT - Cognitive decline OT - Dementia OT - Hearing loss OT - Laterality OT - Presbycusis OT - related hearing loss COIS- Justin S. Golub received travel expenses for industry-sponsored meetings (Cochlear, Advanced Bionics, Oticon Medical), consulting fees or honoraria (Oticon Medical, Auditory Insight, Optinose, Abbott, Decibel Therapeutics, Alcon), department received unrestricted educational grants (Storz, Stryker, Acclarent, 3NT, Decibel Therapeutics). EDAT- 2022/02/17 00:00 MHDA- 2022/02/17 00:01 PMCR- 2022/02/17 CRDT- 2024/03/22 04:00 PHST- 2021/09/15 00:00 [received] PHST- 2021/12/12 00:00 [accepted] PHST- 2022/02/17 00:01 [medline] PHST- 2022/02/17 00:00 [pubmed] PHST- 2024/03/22 04:00 [entrez] PHST- 2022/02/17 00:00 [pmc-release] AID - 10.1097/ONO.0000000000000008 [doi] PST - epublish SO - Otol Neurotol Open. 2022 Feb 17;2(1):e008. doi: 10.1097/ONO.0000000000000008. eCollection 2022 Mar.