PMID- 38516743 OWN - NLM STAT- Publisher LR - 20240405 IS - 1939-3229 (Electronic) IS - 1939-3210 (Linking) DP - 2024 Mar 22 TI - Tetracycline and sulphonamide residues in farmed fish in Dar es Salaam, Tanzania and human health risk implications. PG - 1-10 LID - 10.1080/19393210.2024.2331106 [doi] AB - In Africa, antibiotic residue investigations in animal food have primarily been focused on meat, neglecting farmed fish. This cross-sectional study conducted in Dar es Salaam, Tanzania, aimed to assess sulphonamide and tetracycline residues in farmed fish, comparing levels with Codex Alimentarius Commission's acceptable daily intake (ADI) and maximum residue limits (MRLs). A total of 84 farmed fish were sampled and analysed in the presence of tetracycline and sulphonamide residues. All samples were positive for sulphonamide residues (100%; n = 84), and 2.4% (n = 2) were positive for tetracycline and consequently also positive for both compounds. Tetracycline levels were below ADI and MRL, 28.5% (n = 24) surpassed the ADI, and 6% (n = 5) of the samples exceeded the MRL for sulphonamide. Regular monitoring of antibiotic residues in aquaculture products is crucial to mitigate health risks and expanding assessments to include other commonly used compounds is warranted. FAU - Kilusungu, Zainabu H AU - Kilusungu ZH AD - Department of Aquaculture and Fisheries Science, Africa Centre of Excellence in Aquaculture and Fisheries (AquaFish), Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi. FAU - Kassam, Daud AU - Kassam D AD - Department of Aquaculture and Fisheries Science, Africa Centre of Excellence in Aquaculture and Fisheries (AquaFish), Lilongwe University of Agriculture and Natural Resources, Lilongwe, Malawi. FAU - Kimera, Zuhura Idd AU - Kimera ZI AD - Department of Environmental and Occupational Health, School of Public Health and Social Sciences, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. FAU - Mgaya, Fauster X AU - Mgaya FX AD - Department of Microbiology and Immunology, School of Diagnostic Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. FAU - Nandolo, Wilson AU - Nandolo W AD - Department of Animal Science, Lilongwe University of Agriculture and Natural Resources(LUANAR), Lilongwe, Malawi. FAU - Kunambi, Peter P AU - Kunambi PP AD - Department of Microbiology and Immunology, School of Diagnostic Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. FAU - Ulomi, Winstone AU - Ulomi W AD - Testing Department, Directorate of Testing and Calibration, Tanzania Bureau of Standards, Dar es Salaam, Tanzania. FAU - Matee, Mecky I N AU - Matee MIN AD - Department of Microbiology and Immunology, School of Diagnostic Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania. AD - SACIDS Foundation for One Health (SACIDS), Sokoine University of Agriculture (SUA), Morogoro, Tanzania. LA - eng PT - Journal Article DEP - 20240322 PL - England TA - Food Addit Contam Part B Surveill JT - Food additives & contaminants. Part B, Surveillance JID - 101317183 SB - IM OTO - NOTNLM OT - Aquaculture OT - Dar es Salaam OT - residues OT - sulphonamides OT - tetracycline EDAT- 2024/03/22 06:44 MHDA- 2024/03/22 06:44 CRDT- 2024/03/22 04:53 PHST- 2024/03/22 06:44 [pubmed] PHST- 2024/03/22 06:44 [medline] PHST- 2024/03/22 04:53 [entrez] AID - 10.1080/19393210.2024.2331106 [doi] PST - aheadofprint SO - Food Addit Contam Part B Surveill. 2024 Mar 22:1-10. doi: 10.1080/19393210.2024.2331106.