PMID- 38537063
OWN - NLM
STAT- Publisher
LR  - 20240327
IS  - 1538-943X (Electronic)
IS  - 1058-2916 (Linking)
DP  - 2024 Mar 28
TI  - Impella as Bridge to Durable Left Ventricular Assist Device in Acute Myocardial 
      Infarction Cardiogenic Shock Patients.
LID - 10.1097/MAT.0000000000002201 [doi]
AB  - Implantation of durable left ventricular assist device (LVAD) in cardiogenic 
      shock (CS) patients after acute myocardial infarction (AMI) poses specific 
      challenges (small left ventricular size, acute infarct area, need for 
      antithrombotic therapy, status Interagency Registry for Mechanically Assisted 
      Circulatory Support (INTERMACS) 1 with impaired organ function and derangements 
      in coagulation and inflammatory parameters) which may affect outcomes. We 
      reviewed data of all AMI-CS patients who were implanted LVAD after Impella 
      support at a referral center with the aim to analyze feasibility, timing, and 
      outcomes of durable LVAD implantation after tMCS with Impella due to AMI-CS. 
      Twenty-one patients were treated between 2013 and 2023: all were in Society for 
      Cardiovascular Angiography & Interventions (SCAI) class D-E and INTERMACS 1-2 at 
      presentation, median LV ejection fraction (EF) and LV end-diastolic diameter 
      (EDD) were 15 (10-20)% and 57 (54-60) mm, respectively. Eleven patients (52%) 
      were supported with Impella CP, seven with Impella 5.0 (33%), and three (14%) 
      with Impella 2.5. Axillary cannulation was performed in nine patients (43%). Five 
      patients (24%) had concomitant venoarterial extracorporeal membrane oxygenation 
      (VA-ECMO) support. Median duration of Impella support was 12 (8-14) days. 
      Overall, the use of Impella was characterized by low rate of complications and 
      allowed successful bridge to durable LVAD in all patients, with 100% 30 day 
      survival rate.
CI  - Copyright (c) ASAIO 2024.
FAU - Ajello, Silvia
AU  - Ajello S
AD  - From the Cardiac Intensive Care Unit, Istituto di Ricovero e Cura a Carattere 
      Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy.
FAU - Pieri, Marina
AU  - Pieri M
AUID- ORCID: 0000-0002-4101-800
AD  - Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific 
      Institute, Milan Italy.
AD  - School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
FAU - Dormio, Sara
AU  - Dormio S
AD  - Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific 
      Institute, Milan Italy.
FAU - Baldetti, Luca
AU  - Baldetti L
AD  - From the Cardiac Intensive Care Unit, Istituto di Ricovero e Cura a Carattere 
      Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy.
FAU - Altizio, Savino
AU  - Altizio S
AD  - From the Cardiac Intensive Care Unit, Istituto di Ricovero e Cura a Carattere 
      Scientifico (IRCCS) San Raffaele Scientific Institute, Milan, Italy.
FAU - Consolo, Filippo
AU  - Consolo F
AD  - School of Medicine, Vita-Salute San Raffaele University, Milan, Italy.
FAU - Nardelli, Pasquale
AU  - Nardelli P
AD  - Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific 
      Institute, Milan Italy.
FAU - Ortalda, Alessandro
AU  - Ortalda A
AD  - Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific 
      Institute, Milan Italy.
FAU - Scandroglio, Anna Mara
AU  - Scandroglio AM
AD  - Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific 
      Institute, Milan Italy.
LA  - eng
PT  - Journal Article
DEP - 20240328
PL  - United States
TA  - ASAIO J
JT  - ASAIO journal (American Society for Artificial Internal Organs : 1992)
JID - 9204109
SB  - IM
COIS- Disclosure: M.P., S. Alticcio, P.N., A.O., and A.M.S. received speaker fee by 
      Abiomed GmbH. M.P. received consultancy fee by Abiomed GmbH. The other authors 
      have no conflicts of interest to report.
EDAT- 2024/03/27 18:45
MHDA- 2024/03/27 18:45
CRDT- 2024/03/27 15:23
PHST- 2024/03/27 18:45 [medline]
PHST- 2024/03/27 18:45 [pubmed]
PHST- 2024/03/27 15:23 [entrez]
AID - 00002480-990000000-00452 [pii]
AID - 10.1097/MAT.0000000000002201 [doi]
PST - aheadofprint
SO  - ASAIO J. 2024 Mar 28. doi: 10.1097/MAT.0000000000002201.