PMID- 3873474 OWN - NLM STAT- MEDLINE DCOM- 19850719 LR - 20190908 IS - 0271-6798 (Print) IS - 0271-6798 (Linking) VI - 5 IP - 3 DP - 1985 May-Jun TI - Histocompatibility antigens in Osgood-Schlatter disease. PG - 302-5 AB - Eighteen unrelated children (12 boys and six girls) with Osgood-Schlatter disease (OSD) were evaluated by history, physical examination, and histocompatibility antigen [human leukocyte antigen (HLA)] determination. Four boys and two girls had pain at sites other than the tibial tuberosity. By history, other related individuals with a diagnosis of OSD were found in six of the 18 families. The distributions of HLA antigens (A, B, and DR) were not demonstrably abnormal. The similarity of OSD and enthesitis accompanying HLA-B27-associated arthropathy may cause diagnostic difficulty. The lack of an association between OSD and HLA-B27 may be of assistance in differentiating the two disorders. FAU - Sherry, D D AU - Sherry DD FAU - Petty, R E AU - Petty RE FAU - Tredwell, S AU - Tredwell S FAU - Schroeder, M L AU - Schroeder ML LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - United States TA - J Pediatr Orthop JT - Journal of pediatric orthopedics JID - 8109053 RN - 0 (HLA Antigens) RN - 0 (HLA-B27 Antigen) RN - 0 (Histocompatibility Antigens Class II) SB - IM MH - Adolescent MH - Child MH - Diagnosis, Differential MH - Female MH - HLA Antigens/*genetics MH - HLA-B27 Antigen MH - Histocompatibility Antigens Class II/genetics MH - Humans MH - Male MH - Osteochondritis/diagnosis/*genetics MH - Spondylitis, Ankylosing/diagnosis EDAT- 1985/05/01 00:00 MHDA- 1985/05/01 00:01 CRDT- 1985/05/01 00:00 PHST- 1985/05/01 00:00 [pubmed] PHST- 1985/05/01 00:01 [medline] PHST- 1985/05/01 00:00 [entrez] AID - 10.1097/01241398-198505000-00009 [doi] PST - ppublish SO - J Pediatr Orthop. 1985 May-Jun;5(3):302-5. doi: 10.1097/01241398-198505000-00009.