PMID- 3877448
OWN - NLM
STAT- MEDLINE
DCOM- 19851125
LR  - 20190622
IS  - 0002-9149 (Print)
IS  - 0002-9149 (Linking)
VI  - 56
IP  - 12
DP  - 1985 Nov 1
TI  - Determination of left ventricular mass using single-photon emission computed 
      tomography.
PG  - 761-4
AB  - To test the hypothesis that single-photon emission computed tomography (SPECT) 
      could actually determine left ventricular LV mass in humans, SPECT measurements 
      of LV mass were compared with LV mass determined by cineangiography in 12 
      patients with normal coronary arteries and LV function. Repeat SPECT 
      determinations of LV mass were carried out in 5 patients. Projection images of 
      the left ventricle were acquired after intravenous injection of thallium-201 
      (TI-201) using a rotating gamma camera. Transverse sections were reconstructed by 
      filtered backprojection. The boundary of LV uptake of TI-201 in each transverse 
      section was defined using a 3-dimensional threshold detector. Scintigraphic LV 
      mass (total number of voxels demonstrating LV TI-201 uptake X voxel volume X 
      specific gravity of myocardium) was compared with angiographic LV mass. There was 
      good correlation between LV mass determined by SPECT and that determined by 
      cineangiography. Mean angiographic LV mass was 208 +/- 45 g (+/- standard 
      deviation). Mean SPECT LV mass was 204 +/- 42 g. Linear regression analysis 
      revealed the following relation: SPECT LV mass = 0.76 X angiographic LV mass + 
      46.1 (r = 0.82, root-mean-square deviation from regression = 24.7). The SPECT 
      values of LV mass varied an average of 10.4 +/- 4.6% (+/- standard deviation) in 
      the 5 patients in whom 2 determinations were made. Thus, SPECT of TI-201 can 
      accurately measure LV mass in humans.
FAU - Wolfe, C L
AU  - Wolfe CL
FAU - Jansen, D E
AU  - Jansen DE
FAU - Corbett, J R
AU  - Corbett JR
FAU - Lipscomb, K
AU  - Lipscomb K
FAU - Gabliani, G
AU  - Gabliani G
FAU - Filipchuk, N
AU  - Filipchuk N
FAU - Redish, G
AU  - Redish G
FAU - Lewis, S E
AU  - Lewis SE
FAU - Willerson, J T
AU  - Willerson JT
LA  - eng
GR  - HL-17669/HL/NHLBI NIH HHS/United States
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PT  - Research Support, U.S. Gov't, P.H.S.
PL  - United States
TA  - Am J Cardiol
JT  - The American journal of cardiology
JID - 0207277
SB  - IM
MH  - Heart Ventricles/anatomy & histology/*diagnostic imaging
MH  - Humans
MH  - Radiography
MH  - *Tomography, Emission-Computed
EDAT- 1985/11/01 00:00
MHDA- 1985/11/01 00:01
CRDT- 1985/11/01 00:00
PHST- 1985/11/01 00:00 [pubmed]
PHST- 1985/11/01 00:01 [medline]
PHST- 1985/11/01 00:00 [entrez]
AID - 0002-9149(85)91131-2 [pii]
AID - 10.1016/0002-9149(85)91131-2 [doi]
PST - ppublish
SO  - Am J Cardiol. 1985 Nov 1;56(12):761-4. doi: 10.1016/0002-9149(85)91131-2.