PMID- 3891646
OWN - NLM
STAT- MEDLINE
DCOM- 19850802
LR  - 20131121
IS  - 0172-4622 (Print)
IS  - 0172-4622 (Linking)
VI  - 6
IP  - 2
DP  - 1985 Apr
TI  - Effects of muscle CHO-loading manipulations on hormonal responses during 
      prolonged exercise.
PG  - 95-9
AB  - This study examined the effects of a pre-experimental period of muscle 
      carbohydrate (CHO)-loading manipulations followed by a 24-h CHO-poor diet, 
      intended to increase muscle glycogen content and reduce hepatic glycogen levels, 
      on substrate and endocrine responses during a period of prolonged exercise. Seven 
      subjects pedaled a cycle ergometer for 70 min at 64% leg VO2max (1) after normal 
      CHO intake (CHON) and (2) after leg muscle CHO loading (CHOL), both of these 
      procedures being followed by a period of arm exercise (70 min; 70% arm VO2max) 
      and 24 h CHO-poor intake. CHON, as compared to CHOL condition, resulted in 
      greater blood concentrations of free fatty acids (1.8 vs 1.3 mmol X L-1), 
      glycerol (0.41 vs 0.28 mmol X L-1), norepinephrine (2.2 vs 1.5 ng X ml-1), 
      epinephrine (0.90 vs 0.27 ng X ml-1), and cortisol (47 vs 23 g X dl-1) at min 70 
      of exercise. Insulin concentrations during exercise showed a strong tendency to 
      be lower in CHON than in CHOL condition, although the differences were not 
      significant. There were no significant differences between the two conditions in 
      blood glucose, lactate, and glucagon concentrations. These data indicate that 
      muscle CHO-loading manipulations intended to specifically increase the muscle 
      glycogen content are associated with the difference in metabolic adaptation and 
      hormonal changes during exercise.
FAU - Lavoie, J M
AU  - Lavoie JM
FAU - Helie, R
AU  - Helie R
FAU - Peronnet, F
AU  - Peronnet F
FAU - Cousineau, D
AU  - Cousineau D
FAU - Provencher, P J
AU  - Provencher PJ
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Germany
TA  - Int J Sports Med
JT  - International journal of sports medicine
JID - 8008349
RN  - 0 (Blood Glucose)
RN  - 0 (Dietary Carbohydrates)
RN  - 0 (Fatty Acids, Nonesterified)
RN  - 0 (Insulin)
RN  - 0 (Lactates)
RN  - 0 (Liver Glycogen)
RN  - 33X04XA5AT (Lactic Acid)
RN  - 9005-79-2 (Glycogen)
RN  - 9007-92-5 (Glucagon)
RN  - PDC6A3C0OX (Glycerol)
RN  - WI4X0X7BPJ (Hydrocortisone)
RN  - X4W3ENH1CV (Norepinephrine)
RN  - YKH834O4BH (Epinephrine)
SB  - IM
MH  - Adult
MH  - Blood Glucose/metabolism
MH  - Dietary Carbohydrates/*metabolism
MH  - Epinephrine/blood
MH  - Exercise Test
MH  - Fatty Acids, Nonesterified/blood
MH  - Glucagon/blood
MH  - Glycerol/metabolism
MH  - Glycogen/*metabolism
MH  - Heart Rate
MH  - Humans
MH  - Hydrocortisone/blood
MH  - Insulin/blood
MH  - Lactates/blood
MH  - Lactic Acid
MH  - Liver Glycogen/metabolism
MH  - Male
MH  - Muscles/*metabolism
MH  - Norepinephrine/blood
MH  - Oxygen Consumption
MH  - *Physical Exertion
EDAT- 1985/04/01 00:00
MHDA- 1985/04/01 00:01
CRDT- 1985/04/01 00:00
PHST- 1985/04/01 00:00 [pubmed]
PHST- 1985/04/01 00:01 [medline]
PHST- 1985/04/01 00:00 [entrez]
AID - 10.1055/s-2008-1025821 [doi]
PST - ppublish
SO  - Int J Sports Med. 1985 Apr;6(2):95-9. doi: 10.1055/s-2008-1025821.