PMID- 3949413
OWN - NLM
STAT- MEDLINE
DCOM- 19860421
LR  - 20190816
IS  - 0020-5915 (Print)
IS  - 0020-5915 (Linking)
VI  - 79
IP  - 4
DP  - 1986
TI  - The excretion of IgE with feces from healthy individuals and from others with 
      allergy and diseases affecting the intestinal tract.
PG  - 357-64
AB  - In this study we looked for the occurrence of immunoglobulin E (IgE) in feces 
      from healthy individuals and determined the total daily excretion and day-to-day 
      variation in IgE in feces from patients with allergy, as well as the correlation 
      between concentrations of IgE in small samples of feces and the total amounts of 
      IgE in feces collected over a longer period. Concentrations of IgE in extracts of 
      small samples of dry feces correlated well with the total daily amounts of IgE in 
      feces collected over a 3-day period. Thus, single small samples of feces can be 
      used to measure the excretion of IgE with feces at that time. In 3 children, 
      studied over a 5-week period, the IgE excretion varied somewhat from one day to 
      another, but was largely within a certain range of concentrations. Addition of 
      trypsin inhibitor to fresh feces had no influence on the IgE concentrations of 
      the resulting fecal extracts. Less than 10% of 88 presumably healthy infants, 
      children, and adults had detectable IgE in their feces, while 21 of 40 children 
      with various kinds of allergy had measurable fecal IgE. Only 3 of 13 individuals 
      who were suffering from infectious acute gastroenteritis had IgE-positive fecal 
      extracts. This was also the case for 6 of 25 adult patients in clinical remission 
      of ulcerative colitis or Crohn's disease. Seven of 14 adult patients with chronic 
      pancreatitis had measurable IgE in feces, and the concentrations were up to ten 
      times the upper limit of IgE found in healthy individuals.(ABSTRACT TRUNCATED AT 
      250 WORDS)
FAU - Kolmannskog, S
AU  - Kolmannskog S
FAU - Florholmen, J
AU  - Florholmen J
FAU - Flaegstad, T
AU  - Flaegstad T
FAU - Kildebo, S
AU  - Kildebo S
FAU - Haneberg, B
AU  - Haneberg B
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - Switzerland
TA  - Int Arch Allergy Appl Immunol
JT  - International archives of allergy and applied immunology
JID - 0404561
RN  - 37341-29-0 (Immunoglobulin E)
SB  - IM
MH  - Adolescent
MH  - Child
MH  - Child, Preschool
MH  - Chronic Disease
MH  - Colitis, Ulcerative/*immunology
MH  - Crohn Disease/*immunology
MH  - Feces/*immunology
MH  - Gastroenteritis/immunology
MH  - Humans
MH  - Hypersensitivity/*immunology
MH  - Immunoglobulin E/*analysis
MH  - Infant
MH  - Pancreatitis/*immunology
MH  - Temperature
EDAT- 1986/01/01 00:00
MHDA- 1986/01/01 00:01
CRDT- 1986/01/01 00:00
PHST- 1986/01/01 00:00 [pubmed]
PHST- 1986/01/01 00:01 [medline]
PHST- 1986/01/01 00:00 [entrez]
AID - 10.1159/000234002 [doi]
PST - ppublish
SO  - Int Arch Allergy Appl Immunol. 1986;79(4):357-64. doi: 10.1159/000234002.