PMID- 3962588
OWN - NLM
STAT- MEDLINE
DCOM- 19860425
LR  - 20190812
IS  - 0001-6322 (Print)
IS  - 0001-6322 (Linking)
VI  - 69
IP  - 1-2
DP  - 1986
TI  - Pathology of skeletal muscle and intramuscular nerves in infantile neuroaxonal 
      dystrophy.
PG  - 117-23
AB  - Biopsies of the biceps muscle and sural nerve were taken from a girl aged 2 years 
      with infantile neuroaxonal dystrophy (INAD). In addition to the typical axonal 
      spheroid bodies in a number of the i.m. nerve fibers, the neuromuscular junctions 
      (NMJs) and motor nerve endings also contained axonal swellings. The sural nerve, 
      except for three dystrophic fibers, was almost completely normal. A teased nerve 
      preparation showed four additional abnormal fibers with focal axonal enlargement 
      similar to those in giant axonal neuropathy (GAN). These results suggest that a 
      biceps muscle biopsy may be more useful than a sural nerve biopsy for the 
      diagnosis of INAD, because the muscle contains abnormal peripheral nerves and 
      NMJs in high frequency.
FAU - Miike, T
AU  - Miike T
FAU - Ohtani, Y
AU  - Ohtani Y
FAU - Nishiyama, S
AU  - Nishiyama S
FAU - Matsuda, I
AU  - Matsuda I
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Germany
TA  - Acta Neuropathol
JT  - Acta neuropathologica
JID - 0412041
SB  - IM
MH  - *Axons/enzymology
MH  - Child, Preschool
MH  - Female
MH  - Humans
MH  - Microscopy, Electron
MH  - Muscles/enzymology/*pathology
MH  - Nervous System Diseases/enzymology/*pathology
MH  - Neuromuscular Junction/ultrastructure
MH  - Peripheral Nerves/*pathology
MH  - Syndrome
EDAT- 1986/01/01 00:00
MHDA- 1986/01/01 00:01
CRDT- 1986/01/01 00:00
PHST- 1986/01/01 00:00 [pubmed]
PHST- 1986/01/01 00:01 [medline]
PHST- 1986/01/01 00:00 [entrez]
AID - 10.1007/BF00687047 [doi]
PST - ppublish
SO  - Acta Neuropathol. 1986;69(1-2):117-23. doi: 10.1007/BF00687047.